Review of the Potential use of Poly (lactic-co-glycolic acid) as Scaffolds in Bone Tissue Recovery

Authors

Kushendarsyah Saptaji, Department of Mechanical Engineering, Faculty of Engineering and Technology, Sampoerna University, Jakarta Selatan 12780, IndonesiaFollow
Asriyanti Asriyanti, Department of Aerospace and Mechanical Engineering, The University of Arizona, Tucson AZ 85721, USA
Nisa Khoiriyah, Department of Aerospace and Mechanical Engineering, The University of Arizona, Tucson AZ 85721, USA
Laely Muryanti, Department of Aerospace and Mechanical Engineering, The University of Arizona, Tucson AZ 85721, USA
Iwan Setiawan, Department of Information System, Faculty of Engineering and Technology, Sampoerna University, Jakarta Selatan, 12780, Indonesia

Abstract

Scaffolds are used as temporary tissue in the human body to expedite healing. Biocompatible materials play a vital role in the field of tissue engineering. Therefore, they can be used to reduce human pain as soon as possible. Polymeric materials are widely used to replicate bone tissue. Poly(lactic-co-glycolic acid) (PLGA) is a potential material for bone tissue scaffolds because of its superior properties, including compatibility with the human body. Accordingly, adding hydroxyapatite and introducing different fabrication methods can enable the production of PLGA scaffolds with good abilities to help cells grow, expand, differentiate, and proliferate. The paper reviews the current development of the biocompatible material PLGA as bone tissue scaffolds. It focuses on the applications, properties, improvements, and sustainability of PLGA.

Recommended Citation

Saptaji, Kushendarsyah; Asriyanti, Asriyanti; Khoiriyah, Nisa; Muryanti, Laely; and Setiawan, Iwan (2024) "Review of the Potential use of Poly (lactic-co-glycolic acid) as Scaffolds in Bone Tissue Recovery," Makara Journal of Science: Vol. 28: Iss. 1, Article 4.
DOI: 10.7454/mss.v28i1.1496
Available at: https://scholarhub.ui.ac.id/science/vol28/iss1/4