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Abstract

This study investigated the catalytic ability of ZrOCl2∙8H2O as a mild, environmentally benign nature, and economical catalyst for the multi-component efficient synthesis of biologically active highly substituted dihydro-2-oxopyrrole derivatives with excellent yields and short reaction times. This procedure has several advantages, including use of mild, nontoxic, and inexpensive catalysts, one-pot synthesis, environmentally benign nature, simple operational procedure, and highly efficient conditions.

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