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Abstract

The investigation for antifungal effect of medicinal plants, combination infusion of Piper bettle leaves, Punica granatum Fructus Cortec, Curcuma domestica Rhizome. The tested demartophyta used Candida albicans. This research using dilution method to determine of minimum inhibitory concentration (MIC) and difusion method to determine zone inhibition around of disc. The results of determination of MIC showed that combination infusion Piper bettle leaves with Punica granatum Fructus Cortex against C. albicans respectively, 31,2 mg/ml : 7,8 mg/ml; 15,6 mg/ml : 15,6 mg/ml and 7,8 mg/ml : 31,2 mg/ml. The determination for zone inhibition from 3 concentration of infusion of Piper bettle leaves with 3 concentration of Punica granatum Fructus Cortex with 9 combination against C. albicans showed that combination of two infusion is the larger than the single infusion.

References

[1] K. Heyne Tumbuhan Berguna Indonesia II, Badan Penelitian dan Pengembangan Kehutanan. Departemen Kesehatan Republik Indonesia, Jakarta, 1987. [2] Hernani, S. Yuliani. Peranan Sirih Sebagai Obat Tradisional. Prosiding Seminar Sirih, Yogyakarta, 1991. [3] SD. Suprihatin. Candida dan Kandidiasis Pada Manusia, FK UI, Jakarta, 1992. [4] T. Danielle, KS Pudji, AA. Sumarni. Majalah Parasitologi Indonesia 7 (1994). [5] V. Lorian, Antibiotics in Laboratory Medicine, 2nd. Ed., Williamsand Wilkins, London, 1980

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