Antioxidant Constituents from the Bark of Aglaia eximia (Meliaceae)

Authors

Julinton Sianturi, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, Indonesia
Kindi Farabi, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, Indonesia
Tri Mayanti, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, Indonesia
Desi Harneti, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, Indonesia
Darwati, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, Indonesia
Unang Supratman, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang 45363, IndonesiaFollow
Khalijah Awang, Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 59100, Malaysia
Hideo Hayashi, Division of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Gakuen-cho, Sakai, Osaka 599-8531, Japan

Abstract

The genus Aglaia is a a rich source of different compounds with interesting biological activities. A part of our continuing search for novel biologically active compounds from Indonesia Aglaia plants, the ethyl acetate extract of bark of Aglaia eximia showed significant antioxidant activity. Four antioxidant compounds, kaempferol (1), kaempferol-3-O-α-L-rhamnoside (2), kaempferol-3-O-β-D-glucoside (3) and kaempferol-3-O-β-D-glucosyl-(1→4)-α-L-rhamnoside (4) were isolated from the bark of Aglaia eximia (Meliaceae). The chemical structures of compounds 1-4 were identified on the basis of spectroscopic datas including UV, IR, NMR and MS along with by comparison with those spectra datas previously reported. All compounds showed DPPH radical-scavenging activity with IC50 values of 1.18, 6.34, 8.17, 10.63 mg/mL, respectively.

Recommended Citation

Sianturi, Julinton; Farabi, Kindi; Mayanti, Tri; Harneti, Desi; Darwati; Supratman, Unang; Awang, Khalijah; and Hayashi, Hideo (2016) "Antioxidant Constituents from the Bark of Aglaia eximia (Meliaceae)," Makara Journal of Science: Vol. 20: Iss. 1, Article 1.
DOI: 10.7454/mss.v20i1.5655
Available at: https://scholarhub.ui.ac.id/science/vol20/iss1/1