•  
  •  
 

Abstract

Encapsulated Ketoprofen by Chitosan-Alginat based on Type and Variation of Tween 80 and Span 80 Concentration. Ketoprofen has been encapsulated by chitosan-alginate based on types of surfactant and it’s concentration. The variations of concentration either Tween 80 (polietilena sorbitanmonooleat) or Span 80 (sorbitanmonooleat) that used were around (1- 3)% concentrations with stirring around (15-60) minutes. The using of Tween 80 resulted efficiency of encapsulated ketoprofen and nano particle size (100-1000) nm are higher than Span 80.

References

[1] T. Yamada, H. Onishi, Y. Machida, Yakugaku Zasshi. 121 (2001) 239. [2] P. Sugita, A. Sjahriza, S.I. Lestari, J. Natur. 9 (2006a) 32. [3] P. Sugita, A. Sjahriza, D. Wahyono, J. Sains dan Teknologi. 8 (2006b) 133. [4] A. Cardenas, W.A. Monal, F.M. Goycoolea, I.H. Cia-para, C. Peniche, Macromol Biosci. 3 (2003) 535. [5] T.W. Tan, B. Hu, J. Xian-Hua, Z. Mu, Journal of Bioactive and Compatible Polymers. 18 (2003) 207. [6] P. Sugita, A. Sjahriza, Rachmanita, J. Alchemy. 6 (2007a) 57. [7] P. Sugita, A. Sjachriza, D.W. Utomo, Prosiding 1st International Conference on Chemical Sciences, Yogyakarta, 2007b, MAT/33-4. [8] T. Wang, M. Turhan, S. Gunasekaram, Polym. Int. 53 (2004) 911. [9] P. Sugita, B. Srijanto, F. Amelia, B. Arifin, Seminar bersama ITB - UKM Malaysia, Bandung, 2007c. [10] F. Nata, P. Sugita, A. Syahriza. Prosiding International Conference and Workshop on Basic and Applied Science 2007, Surabaya-Indonesia, 2007, p. 297. [11] P. Sugita, S.S. Achmadi, Y. Yundhana. J. Natur, 2010 ( Inpress). [12] P. Sugita, R.S. Asnel, B. Arifin, T. Wukirsari, J. Indonesian of Chemistry, 2010 (Inpress). [13] B.D. Aryanto, Skripsi Sarjana, Fakultas Matematika dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor, Indonesia, 2010. [14] P. Sugita, Y.A. Setyani, B. Srijanto, T. Wukirsari, J. Controlled Release, 2010 (Inpress). [15] A.H. Morrish, The Physical Principles of Magnetism, IEEE Press, Newyork, 2001. [16] Hartig et al. Pharm Research. 24 (2007) 12. [17] V.J. Mohanraj, Y. Chen. J. Pharmaceuticals Research. 5 (2006) 561. [18] X. Yongmei, D. Yumin, International Journal of Pharmaceutics. 250 (2003) 215. [19] J. Jiao, J.D. Burgess, The AAPS Pharm. Sci. 5 (2003) Artikel 7. [20] Silva et al., The AAPS Journal. 7 (2006) Article 88

Download
COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.