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Abstract

Enterotoxin Escherichia coli resistant to antibiotics on broiler. The used of antibiotics should be re- evaluated, as well as over Escherichia coli enterotoxin. Plants meniran (Phyllanthus niruri Linn) is a plant that can be used as an alternative prevention and treatment of diseases caused by Escherichia coli enterotoxin. In this research, broilers at the age of 23 days were divided into six groups. Two groups are positive control was infected by Escherichia coli and negative control was not infected by Escherichia coli. Three groups are extract of Phyllanthus niruri Linn. plant that variety in three dosage: 20%, 25%, 30% and antibiotic. After five days treatment the broiler was to take the sample of blood tissue. The data were tested with Annova and continued by Duncan multiple range test. There was a significant difference of immunomodulation activity between treatment group doses 30% has been able to decrease lymphocyte on blood. The result showed doses 30% can be used as immunomodulation to Escherichia coli.

Bahasa Abstract

Enterotoxin Escherichia coli resisten terhadap antibiotik pada ayam pedaging. Penggunaan antibiotik harus dievaluasi ulang, begitu juga Escherichia coli enterotoksin. Tanaman meniran (Phyllanthus niruri Linn) merupakan tanaman yang bisa dijadikan alternatif pencegahan dan pengobatan penyakit yang disebabkan oleh Escherichia coli enterotoksin. Dalam penelitian ini, ayam broiler pada umur 23 hari dibagi menjadi enam kelompok. Dua kelompok kontrol positif terinfeksi oleh Escherichia coli dan kontrol negatif tidak terinfeksi oleh Escherichia coli. Tiga kelompok adalah ekstrak Phyllanthus niruri Linn. Tanamlah varietas itu dalam tiga dosis: 20%, 25%, 30% dan antibiotik. Setelah lima hari pengobatan ayam pedaging tersebut mengambil sampel jaringan darah. Data diuji dengan Annova dan dilanjutkan dengan uji Duncan multiple range. Ada perbedaan yang signifikan antara aktivitas imunomodulasi antara dosis kelompok perlakuan 30% yang mampu menurunkan limfosit pada darah. Hasilnya menunjukkan dosis 30% dapat digunakan sebagai imunomodulasi ke Escherichia coli.

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