"Introduction. Untreated ureteropelvic junction obstruction would lead to infection and many other complications. The gold standard to treat this condition is pyeloplasty. Nowadays, laparoscopic pyeloplasty has emerged as a potential modality better than open pyeloplasty. Method. Data retrospectively obtained from the medical records of UPJO patients at Persahabatan Hospital, Jakarta. The patient’s age, gender, weight, and BMI noted. Duration of operation, intraoperative blood loss, and complications recorded as the intraoperative status. Length of hospital stay, pain score on the first post-operative day, time to do the daily activity, and return to work recorded as post-operative variables of this study. Results. We included our ten patients who underwent laparoscopic pyeloplasty in our center. The mean of patient’s age is 40.3 ± 17.1 years with 70% male patients. The average body weight and body mass indexes are 62.7 ± 17.8 kg and 24.2 ± 3.9 kg/m2, respectively. Most of the procedures have been done in 225 minutes. Intraoperative blood loss is around 50 mL, with one patient loss his blood around 500 mL. Describing the post-operative outcomes, the average length of stay of the patients is 8.6 ± 1.6 days, with an average visual analog score of 3.5 ± 1.1 on the first post-operative day. The average time needed to recover to daily activity is around 7.3 ± 1.8 days. Conclusion. This study describes our initial experience on laparoscopic pyeloplasty in RSUP Persahabatan Jakarta. The data showed comparable results with other reviews. We need to bring further improvement to our findings along with our experience" by Hardian Gunardi and Diani Kartini
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Abstract

Introduction. Obesity is an independent risk factor and prognostic factor of primary breast cancer. Abundant adipose tissue would lead to increment of blood estrogen level; thus, promoting proliferation of cancer cell, especially those with positive estrogen receptor (ER) and progesterone receptor (PR). No study reported the association between obesity and hormone receptor characteristics of primary breast cancer in Indonesia.

Method. We collected cases of primary breast cancer which is diagnosed and undergone immunohistochemistry examination at Cipto Mangunkusumo General Hospital in 2017. The subjects divided into obese group and non-obese group. The ER and PR characteristics of both groups were compared

Results. We collected 202 cases of primary breast cancer, with 89 cases (44%) in obese group and 113 cases (56%) in non-obese group. The mean body mass index (BMI) of the subjects was 24.45±4.3. Both groups were similar in terms of age, menopausal status, stage, histopathological morphology and grade. No significant association was found between obesity and ER or PR. We analyzed correlation between BMI and the percentage of expressed hormone receptor, but no correlation was found. This finding did not conform with other Western studies. Difference in characteristics of the subjects and other hormonal factors might contribute to the outcome.

Conclusion. There is no association between obesity and hormone receptor characteristics of primary breast cancer at Cipto Mangunkusumo General Hospital in 2017.

Keywords: obesity, hormone receptor, estrogen, progesterone, primary breast cancer

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