Abstract

Rendahnya asupan yodium berhubungan dengan ekskresi yodium urine (EYU) yang tidak normal. Asupan yodium yang terlalu rendah juga menyebabkan kelenjar tiroid tidak mampu mempertahankan sekresi hormon yang adekuat sehingga timbul hipertrofi tiroid yang menimbulkan goiter. Penelitian ini bertujuan menguji hubungan asupan yodium, EYU, dan goiter pada wanita usia subur (WUS) di daerah endemis defisiensi yodium. Penelitian observasional potong lintang ini dilakukan pada 115 WUS di Kecamatan Prambanan Sleman yang dipilih secara random. Asupan yodium diukur menggunakan metode food recall 24 jam, EYU diukur dengan metode acid digestion, dan goiter diukur dengan cara palpasi. Hubungan antarvariabel dianalisis dengan uji kai kuadrat. Hasil penelitian menunjukkan subjek dengan asupan yodium kurang sebanyak 83,5% dan asupan yodium cukup sebanyak 16,5%. Subjek dengan goiter sebanyak 13% dan tanpa goiter sebanyak 87%. Subjek defisiensi yodium sebanyak 15,7% (tingkat berat 2,6%; tingkat sedang 3,5%; tingkat ringan 9,6%), yang normal sebanyak 31,3%, sedangkan yang lebih sebanyak 20,8% dan ekses sebanyak 32,2%. Asupan yodium berhubungan dengan EYU, tetapi goiter tidak berhubungan dengan asupan yodium dan EYU. The low iodine intake, associated with insufficiency of urinary iodine concentration (UIC). Iodine intake is too low, also causes the thyroid gland is unable to maintain adequate hormone secretion, influence the thyroid hypertrophy that causes goitre. This study aimed to examine the relationship of iodine intake, UIC, and goiter on women of childbearing age in endemic areas of iodine deficiency. This cross-sectional observational study was performed 115 randomly selected women of childbearing age at sub-district of Prambanan, Sleman Regency. Iodine intake was measured using 24-hour food recall method, UIC measured by acid digestion method, and goiter measured by palpation method.The association between variables.

References

1. Tim Gangguan Akibat Kekurangan Yodium Pusat. Rencana aksi nasional kesinambungan program penanggulangan gangguan akibat kurang yodium. Jakarta: Tim Gangguan Akibat Kekurangan Yodium Pusat; 2005. 2. Dinas Kesehatan Kabupaten Sleman. Hasil pemantauan garam beryodium dan pemutakhiran data GAKY Kabupaten Sleman. Sleman: Dinas Kesehatan Kabupaten Sleman; 2003. 3. Mutalazimah, Asyanti S. Angka kecerdasan anak sekolah menurut perspektif kadar yodium dalam urine. Jurnal Nutrisia. 2010; 12(1): 1-7. 4. Stockigt J. Clinical strategies in the testing of thyroid function[monograph on the Internet]. Melbourne (Australia): Monash University and Alfred and Apworth Hospital; 2011 [cited 2011 Dec 26]. Available from: http://www.thyroidmanager.org/wp-content/uploads/chapters/clinical-strategies-in-the-testing-of-thyroid-function.pdf. 5. Bashir S, Shabbir I, Hussain R, Islam M, Aasim M. Thyroid status and urinary iodine levels in women of endemic goiter area. Pakistan J Med Res [serial on the internet]. 2012 [cited 2013 Aug 8]; 51(4):136-8. Available from: http://www.pakmedinet.com/journal/11/1/December/- 2012/51%284%29. 6. Henjum S, Barikmo I, Strand TA, Oshaug A, Torheim LE. Iodineinduced goitre and high prevalence of anaemia among Saharawi refugee women. Public Health Nutr [serial on theInternet]. 2012 [cited 2013 Aug 20]; 15(8): 1512-8. Available from: http://journals.cambridge.- org/download. 7. Burgi H. Iodine excess. Best practice and research clinical endocrinology metabolism [serial on the internet]. 2010 [cited 2010 Dec 20]; 24(1): 107-15. Available from: http://www.ncbi.nlm.nih.gov/pubmed/2017- 2475. 8. Yaman AK, Demirel F, Ermis B, Piskin IE. Maternal and neonatal urinary iodine status and its effect on neonatal TSH levels in a mildly iodine- deficient area. J Clin Res Pediatr Endocrinol [serial on theInternet]. 2013; 5(2): 90-4 [cited 2013 Aug 20]. Available from: http://www.- jcrpe.org/sayilar/46/buyuk/90-94.pdf 9. Vanderpump MPJ. The epidemiology of thyroid disease. British Med Bull [serial on the internet]. 2011; 99: 39-51 [cited 2013 Jun 27]. Available from: http://www.bmb.oxfordjournals.org/content/99/1/39.- full.pdf . 10. Zimmermann MB. Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review. American Journal of Clinical Nutrition [serial on the internet]. 2009 [cited 2010 Dec 26]; 89 (suppl): 668S-72S. Available from: http://ajcn.nutrition.- org/content/89/2/668S.full.pdf+html. 11. Ara G, Boonstra AM, Roy SK, Alam N, Ahmed S, Khatun UHF, et al. Sub clinical iodine deficiency still prevalent in Bangladeshi adolescent girls and pregnant women. Asian Journal of Clinical Nutrition[serial on theInternet]. 2010 [cited 2011 Jan 11]; 2(1): 1-12. Available from: http://edepot.wur.nl/135313. 12. Demers LM, Spencer CA. Laboratory medicine practice guidelines: laboratory support for the diagnosis and monitoring of thyroid disease. Washington: National Academy of Clinical Biochemistry; 2002. 13. Medani AMMH, Elnour AA, Saeed AM. Endemic goitre in the Sudan despite long-standing programmes for the control of iodine deficiency disorders. Bull World Health Org [serial on the Internet]. 2011 [cited 2011 Oct 5]; 89; 121-6. Available from: http://www.who.int/ bulletin/volumes/89/2/09-075002/en/. 14. Badan Pusat Statistik Kabupaten Sleman. Prambanan dalam angka [homepage on the Internet]. Sleman: Badan Pusat Statistik Kabupaten Sleman; 2007 [cited 2011 May 12]. Available from: http: //slemankab. bps.go.id. 15. Watts MJ, O’Reilly J, Marcelli A, Coleman A, Ander EL, Ward NI. A snapshot of environmental iodine and selenium in La Pampa and San Juan provinces of Argentina [monograph on the Internet]. Nottingham (UK): British Geological Survey; 2010 [cited 2013 Aug 21]. Available from: http://epubs.surrey.ac.uk/203304/1/REvised% 20Explo 02071 Argentina_I_Sev2wattsetal.pdf 16. Bashir H, Farooq R, Bhat MH, Majid S. Increased prevalence of subclinical hypothyroidism in females in mountainous valley of Kashmir. Indian J Endocrinol Metab [serial on the Internet]. 2013 [cited 2013 Aug 20]; 17(2): 276-80. Available from: http://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3683204/ 17. Blumenthal N, Byth K, Eastman CJ. Iodine intake and thyroid function in pregnant women in a private clinical practice in Northwestern Sydney before mandatory fortification of bread with iodised salt. Journal Thyroid Res [serial on the internet]. 2012 [cited 2013 Jul 23]:1-6. Available from: http://www.hindawi.com/journals/jtr/2012/798963/. 18. Fuse Y, Ohashi T, Yamaguchi S, Yamaguchi M, Shishiba Y, Irie M. Iodine status of pregnant and postpartum Japanese women: effect of iodine intake on maternal and neonatal thyroid function in an iodine-sufficient area. J Clin Endocrinol Metab [serial on the Internet]. 2011 [cited 2013 Aug 20]; 96(12): 3846-54. Available from: http://www. jcem.endojournals. org. 19. Rhee CM, Bhan I, Alexander EK, Brunelli SM. Association between iodinated contrast media exposure and incident hyperthyroidism and hypothyroidism. Arch Internal Med [serial on the Internet]. 2012 [cited 2013 Aug 10]; 172(2): 153-9 . Available from: http://archinte.jamanetwork. com/article.aspx?articleid=1108674. 20. Gahche JJ, Bailey RL, Mirel LB, Bailey RL, Mirel LB, Dwyer JT. The prevalence of using iodine-containing supplements is low among reproductive- age women, NHANES 1999-2006. J Nutr [serial on the Internet]. 2013 [cited 2013 Jul 15]; 143(6): 872-7. Available from: http://jn.nutrition.org/content/early/2013/04/24/jn.112.169326.short? rss=1. 21. Aminorroaya A, Janghorbani M, Amini M, Hovsepian S, Tabatabaei A, Fallah Z. The prevalence of thyroid dysfunction in an iodine-sufficient area in Iran.Arch Iranian Medicine [serial on the internet]. 2009; 2(3): 262-70 [cited 2013 Jun 20]. Available from: http://razi.ams.ac.ir/- AIM/NEWPUB/09/12/3/009.htm. 22. Menon VU, Chellan G, Sundaram KR, Murthy S, Kumar H, Unnikrishnan AG, et al. Iodine status and its correlations with age, blood pressure, and thyroid volume in South Indian women above 35 years of age (Amrita thyroid survey). Indian J Endocrinol Metabolism [serial on the Internet]. 2011 [cited 2013 Jun 10]; 15(4): 309-15. Available from: http://www.ijem.in/text.asp?2011/15/4/309/85584.

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