Abstract
Demensia Alzheimer menempati urutan kesembilan penyebab kematian di Amerika Serikat. Demensia adalah kondisi yang sering dialami yang berhubungan dengan berbagai faktor dan gaya hidup terutama diet. Penelitian ini bertujuan untuk mengetahui hubungan defisiensi asupan riboflavin (vitamin B12) dengan demensia pada usia lanjut (usila). Penelitian ini menggunakan desain studi cross sectional dan dilaksanakan pada bulan September 2007 sampai dengan Januari 2008. Sampel penelitian adalah 141 lansia berumur lebih dari sama dengan 60 tahun yang diambil secara purposive sampling. Demensia diukur menggunakan kuesioner MMSE (² 24, skor maksimum 30) dan asupan riboflavin diukur menggunakan form Semi Quantitative – FFQ. Penelitian ini memperlihatkan bahwa 47,5% usila mengalami demensia. Hasil uji statistik menunjukkan bahwa terdapat hubungan yang signifikan antara umur, tingkat pendidikan, dan asupan riboflavin dengan kejadian demensia pada usila (nilai p < 0,05).
Dementia Alzheimer’s was ranked the ninth leading cause of death in The United States. Dementia can not be avoided as related to several factors and lifestyle especially the diet. The objective of this research is to know relation the deficiency of riboflavine (vitamin B12) intake and incidence of dementia at elderly. A cross-sectional study was conducted between September 2007 and January 2008. The sample obtained was 141 elderly which it was conducted to purposive sampling. Dementia was measured by using questionnaire MMSE (² 24, maximum score was 30), and riboflavine intake was measure by Semi Quantitative – FFQ form. This study shows that dementia in elderly was 47,5%. Statistical test showed that Statistical test showed that incidence of dementia had significantly associated with ages, level of education, and riboflavine intake (p value < 0,05).
References
- Feldman G. Death of a senator: life expectancy and causes of death in 20th century US senators. American Journal of Public Health [seri Internet]. 2003 May [diakses tanggal 30 Mei 2007]; Vol. 93, No.5: [p.771]. Diunduh dari: http://www.ajph.org.
- Alzheimers Association. Alzheimer’s facts and figures 2007. 2007. [diakses tanggal 3 April 2007]. Diunduh dari: http://www.demensia-in-europe.eu/.
- Campbell TC, Campbell II TM. China study. Dallas: BenBella Book; 2006.
- Henderson AS. Dementia. Geneva: World Health Organization; 1994.
- World Health Organization. Mental health: new understanding, new hope. Geneva: World Health Organization; 2001.
- World Health Organization. The world health report 2003. Shapping the future. Geneva: World Health Organization; 2003.
- Mooijaart SP, Gussekloo J, Frölich M, Jolles J, Stott DJ, Westendorp RGJ, et al. Homocysteine, vitamin b12, and folic acid and the risk of cognitive decline in old age: the leiden 85-plus study. Am J Clin Nutr. 2005; 82: 866-71. [diakses tanggal 1 Juni 2008]. Diunduh dari: http://www.ajcn.org/.
- Lemeshow S, Hosmer Jr DW, Klar J, Lwanga SK. Besar sampel dalam penelitian kesehatan. Yogyakarta: Gajah Mada University Press; 1997.
- Feng L, Tse-Pin N, Chuah L, Niti M, Kua E. Homocysteine, folate and vitamin b12 and cognitive performance in older chinese adults: findings from the Singapore longitudinal study. Am J Clin Nutr. 2006; 84: 1506- 12.
- Handajani YS. Indeks pengukuran disabilitas dan prediksi kualitas hidup pada masyarakat lanjut usia di DKI Jakarta [disertasi]. Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia; 2006.
- Gibson RS. Principles of nutritional assessment. 2nd ed. New York: Oxfrord University Press; 2005.
- Lembaga Ilmu Pengetahuan Indonesia, Badan Pusat Statistik, Kementerian Kesehatan, Badan Pengawas Obat dan Makanan, Badan Perencanaan dan Pembangunan Nasional, Kementerian Pertanian, et al. Prosiding Widyakarya Nasional Pangan dan Gizi VIII, Ketahanan Pangan dan Gizi di Era Otonomi Daerah dan Globalisasi. Jakarta: Lembaga Ilmu Pengetahuan Indonesia; 2004.
- Kleinbaum, Kupper, Muller. Applied regression analysis and other multivariable methods. 2nd ed. Boston: PWS-Kent Publishing Company; 1998.
- Gillette-Guyonnet S, Nourhashémi F, Andrieu S. Weight loss in alzheimer disease. Am J Clin Nutr. 2000; 71 (suppl): 637S-42S. [diakses tanggal 30 Mei 2007]. Diunduh dari: http://www.ajcn.org/.
- Guérin O, Andrieu S, Schneider SM, Milano M, Boulahssass R, Brocker P, et al. Different modes of weight loss in alzheimer disease: a prospective study of 395 patients, Am J Clin Nutr. 2005; 82: 435–41. [diakses tanggal 1 Juni 2008]. Diunduh dari: http://www.ajcn.org/.
- Yudarini, Rahardjo TBW, Subarkah, Hogervorst E. Profil sosiodemografi dan status kesehatan lansia di daerah urban dan rural Indonesia. Report on seminar ageing, gender health. Jakarta: Centre for Health Research University of Indonesia; 2008.
- World Health Organization. World health statistics 2007. Geneva: World Health Organization; 2007.
- Rahardjo TBW, Yudarini, Subarkah, Dewi VP, Kreager P, Hogervorst E. Mental and social activities and possible dementia among the elderly in three indonesian communities in poster session: spring school on aging oxford institute of ageing. Inggris: University of Oxford; 13-18 April 2008.
- Alzheimer’s Society, LSE, Kings College London. Demensia UK. Summarry of key findings. 2007. [diakses tanggal 3 April 2007]. Diunduh dari: http://www.demensia-in-europe.eu/.
- Lumbantobing. Kecerdasan pada usia lanjut dan demensia. Jakarta: Balai Penerbit Fakultas Kedokteran Universitas Indonesia; 2006.
- Glymour MM, Weuve J, Berkman LF, Kawachi I, Robins JM. Baseline adjustment useful in analyses of change? An example with education and cognitive change. Am J Epidemiol. 2005; 162: 267-78. [diakses tanggal 11 Juni 2008]. Diunduh dari: http://www.aje.oxfordjournals.org/.
- Karp A, Kåreholt I, Qiu C, Bellander T, Winblad B, Laura FL. Relation of education and occupation-based socioeconomic status to incident alzheimer’s disease. Am J Epidemiol. 2004; 159: 175-83. [diakses tanggal 11 Juni 2008]. Diunduh dari: http://www.aje.oxfordjournals.org/.
- Hogervorst E, Sadjimin T, Yesufu A, Kreager P, Rahardjo TB. High tofu intake is associated with worse memory in elderly indonesian men and women, dementia, and geriatric cognitif disorder. S. Basel: Kareger AG; 2008.
- Morris MS, Jacques PF, Rosenberg IH, Selhub J. Folate and vitamin b12 status in relation to anemia, macrocytosis, and cognitive impairment in older americans in the age of folic acid fortification. Am J Clin Nutr. 2007; 85: 193-200. [diakses tanggal 7 Maret 2007]. Diunduh dari: http://www.ajcn.org/.
- Tucker KL, Qiao N, Scott T, Rosenberg I, Spiro III A. High homocysteine and low b vitamins predict cognitive decline in aging men: the veterans affairs normative aging study. Am J Clin Nutr. 2005; 82: 627-35. [diakses tanggal 1 Juni 2008]. Diunduh dari: http://www.ajcn.org/
Recommended Citation
Purnakarya I .
Defisiensi Riboflavin dan Demensia pada Usia Lanjut.
Kesmas.
2011;
6(3):
-
DOI: 10.21109/kesmas.v6i3.99
Available at:
https://scholarhub.ui.ac.id/kesmas/vol6/iss3/1