Abstract
During 2020, the year of the COVID-19 pandemic, different Indonesian provinces had different numbers of COVID-19 infections and fatalities, particularly in West Sumatra Province. This study aimed to investigate the variation of confirmed COVID-19 cases and determine predictors of mortality in hospitalized patients across districts in West Sumatra Province. A retrospective observational study was conducted during the COVID-19 pandemic. From March 2020 to June 2021, 46,005 confirmed cases were collected in the province, of which 42,308 were hospitalized and analyzed. Confirmed cases and deaths were compared by geographic location using spatial analysis. The risk predictors of death were estimated using logistic regression. COVID-19 incidence and mortality varied across cities/districts, with less than 1,000 confirmed cases appearing to be the lowest number. A distinct pattern was visible nonetheless when the incidence density of confirmed cases and deaths was higher. Acute respiratory distress syndrome during the COVID-19 treatment had a higher risk of death (OR = 75.2, 95% CI: 25.6–250). The most significant predictors of death in terms of comorbidity were pneumonia, followed by cancer, chronic obstructive pulmonary disease, diabetes, cardiac disease, and hypertension.
References
1. World Health Organization. WHO Director-General's opening remarks at the media briefing on COVID-19 - 11 March 2020. Geneva: World Health Organization; 2020.
2. World Health Organization. WHO COVID-19 dashboard: World. Geneva: World Health Organization; 2021.
3. World Health Organization. WHO COVID-19 dashboard: Indonesia. Geneva: World Health Organization; 2021.
4. Yu F, Lau L-T, Fok M, et al. COVID-19 Delta variants—Current status and implications as of August 2021. Precis Clin Med. 2021; 4 (4): 287-292. DOI: 10.1093/pcmedi/pbab024.
5. World Health Organization. Novel Coronavirus Disease (COVID-19): Situation Update Report - 65. New Delhi: World Health Organization India; 2021.
6. Ng A. Indonesia reported the highest new Covid cases in the world last week, says WHO. Consumer News and Business Channel (CNBC); 2021.
7. British Broadcasting Corporation (BBC). Covid-19: Indonesia announces lockdown in Java and Bali as cases surge. London: British Broadcasting Corporation (BBC); 2021.
8. Hale T, Angrist N, Hale AJ, et al. Government responses and COVID-19 deaths: Global evidence across multiple pandemic waves. PloS one. 2021; 16 (7): e0253116. DOI:10.1371/journal.pone.0253116.
9. Djalante R, Lassa J, Setiamarga D, et al. Review and analysis of current responses to COVID-19 in Indonesia: Period of January to March 2020. Prog Disaster Sci. 2020; 6: 100091. DOI: 10.1016/j.pdisas.2020.100091.
10. Levin AT, Owusu-Boaitey N, Pugh S, et al. Assessing the burden of COVID-19 in developing countries: Systematic review, meta-analysis and public policy implications. BMJ Glob Health. 2022; 7 (5): e008477. DOI: 10.1136/bmjgh-2022-008477.
11. Gill I, Schellekens P. Covid-19 is a developing country pandemic. Washington, DC: Brookings; 2021.
12. World Health Organization. Estimating mortality from COVID-19: Scientific brief. Geneva: World Health Organization; 2020.
13. Alizadehsani R, Alizadeh Sani Z, Behjati M, et al. Risk factors prediction, clinical outcomes, and mortality in COVID-19 patients. J Med Virol. 2021; 93 (4): 2307-2320. DOI: 10.1002/jmv.26699.
14. Okeahalam C, Williams V, Otwombe K. Factors associated with COVID-19 infections and mortality in Africa: A cross-sectional study using publicly available data. BMJ Open. 2020; 10 (11): e042750. DOI: 10.1136/bmjopen-2020-042750.
15. Dewi R, Kaswandani N, Karyanti MR, et al. Mortality in children with positive SARS-CoV-2 polymerase chain reaction test: Lessons learned from a tertiary referral hospital in Indonesia. Int J Infect Dis. 2021; 107: 78-85. DOI: 10.1016/j.ijid.2021.04.019.
16. Surendra H, Elyazar IR, Djaafara BA, et al. Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study. Lancet Reg Health West Pac. 2021; 9: 100108. DOI: 10.1016/j.lanwpc.2021.100108.
17. Center for Disease Control and Prevention. Geographic differences in COVID-19 cases, deaths, and incidence — United States, February 12–April 7, 2020. MMWR Morb Mortal Wkly Rep. 2020; 69: 465–471. DOI: 10.15585/mmwr.mm6915e4.
18. Shi C, Wang L, Ye J, et al. Predictors of mortality in patients with coronavirus disease 2019: A systematic review and meta-analysis. BMC Infect Dis. 2021; 21 (1): 663. DOI: 10.1186/s12879-021-06369-0.
19. Kementerian Kesehatan Republik Indonesia. Pedoman pencegahan dan pengendalian coronavirus disease 19 (COVID-19) - Revisi 5 (COVID-19 prevention and control guideline - Fifth revision). Jakarta: Kementerian Kesehatan Republik Indonesia; 2020.
20. Pejabat Pengelola Informasi dan Dokumentasi Sumatera Barat. Data pantauan COVID-19 Provinsi Sumatera Barat. Padang: Pejabat Pengelola Informasi dan Dokumentasi Provinsi Sumatera Barat; 2021.
21. Hendarwan H, Syachroni S, Aryastami NK, et al. Assessing the COVID-19 diagnostic laboratory capacity in Indonesia in the early phase of the pandemic. WHO South East Asia J Public Health. 2020; 9 (2): 134-140. DOI: 10.4103/2224-3151.294307.
22. Aisyah DN, Mayadewi CA, Igusti G, et al. Laboratory readiness and response for SARS-Cov-2 in Indonesia. Front Public Health. 2021; 9: 705031. DOI: 10.3389/fpubh.2021.705031.
23. Bonanad C, Garcia-Blas S, Tarazona-Santabalbina F, et al. The effect of age on mortality in patients with COVID-19: A meta-analysis with 611,583 subjects. J Am Med Dir Assoc. 2020; 21 (7): 915-918. DOI: 10.1016/j.jamda.2020.05.045.
24. Berenguer J, Ryan P, Rodriguez-Bano J, et al. Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain. Clin Microbiol Infect. 2020; 26 (11): 1525-1536. DOI: 10.1016/j.cmi.2020.07.024.
25. Hasan SS, Capstick T, Ahmed R, et al. Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: A systematic review and meta-analysis. Expert Rev Respir Med. 2020; 14 (11): 1149-1163. DOI: 10.1080/17476348.2020.1804365.
26. Li X, Ma X. Acute respiratory failure in COVID-19: is it "typical" ARDS? Crit Care. 2020; 24 (1): 198. DOI: 10.1186/s13054-020-02911-9.
27. Zhao D, Yao F, Wang L, et al. A comparative study on the clinical features of coronavirus 2019 (COVID-19) pneumonia with other pneumonias. Clin Infect Dis. 2020; 71 (15): 756-761. DOI: 10.1093/cid/ciaa247.
28. Gattinoni L, Gattarello S, Steinberg I, et al. COVID-19 pneumonia: Pathophysiology and management. Eur Respir Rev. 2021; 30 (162): 210138. DOI: 10.1183/16000617.0138-2021.
29. Mesas AE, Cavero-Redondo I, Álvarez-Bueno C, et al. Predictors of in-hospital COVID-19 mortality: A comprehensive systematic review and meta-analysis exploring differences by age, sex and health conditions. PLoS One. 2020; 15 (11): e0241742. DOI: 10.1371/journal.pone.0241742.
30. da Silva RE, Novaes MRCG, De Oliveira C, et al. National governance and excess mortality due to COVID-19 in 213 countries: A retrospective analysis and perspectives on future pandemics. Global Health. 2023; 19 (1): 80. DOI: 10.1186/s12992-023-00982-1.
31. White P, Crowe C, Bowe A, et al. An audit of COVID-19 death reporting in counties Cork and Kerry, Ireland, winter 2021-2022. Ir J Med Sci. 2023; 192 (4): 1589-1594. DOI: 10.1007/s11845-022-03211-7.
32. Sahay S. Big data and public health: Challenges and opportunities for low and middle income countries. Commun Assoc Inf Syst. 2016; 39 (1): 419 – 438. DOI: 10.17705/1CAIS.03920.
33. Batko K, Ślęzak A. The use of Big Data Analytics in healthcare. J Big Data. 2022; 9 (1): 3. DOI: 10.1186/s40537-021-00553-4.
Recommended Citation
Djafri D , Putri A , Pradipta Y ,
et al.
Variation and Predictors of COVID-19 Mortality in Hospitalized Cases in West Sumatra Province, Indonesia: A Retrospective Observational Study.
Kesmas.
2024;
19(3):
199-208
DOI: 10.21109/kesmas.v19i3.2037
Available at:
https://scholarhub.ui.ac.id/kesmas/vol19/iss3/7