Abstract
Human immunodeficiency virus (HIV) infection has detrimental impacts on the lives of different population groups living with HIV, including men who have sex with men (MSM). Using the World Health Organization Quality of Life questionnaire, this study aimed to assess the health-related quality of life of men living with HIV with different sexual orientations and to determine the dominant influential factors. This cross-sectional study involved 206 men living with HIV. They were recruited from the Sriwijaya Plus Foundation and a medical facility that provided antiretroviral therapy. The data were analyzed using Chi-square and binomial logistic regression. The analysis showed that the percentage of MSM patients was greater than that of non-MSM patients, accounting for 68.9% of the total population. The multivariate logistic regression revealed that the most dominant influential factor was depression status (PR = 5.417; 95% CI = 2.473–11.876), with the majority of the depressed patients being 5.417 times more at risk of a lower quality of life compared to others. These findings suggest that depression can lead to a low quality of life among HIV patients.
References
1. Local Burden of Disease HIV Collaborators. Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems. BMC Med. 2021; 19: 4
2. Local Burden of Disease HIV Collaborators. Subnational mapping of HIV incidence and mortality among individuals aged 15-49 years in sub-Saharan Africa, 2000-18: A modeling study. The Lancet HIV. 2021; 8 (6): e363–e375.
3. United Nations Programme on HIV/AIDS. Global HIV statistics. Geneva: United Nations Programme on HIV/AIDS; 2021.
4. Kementerian Kesehatan Republik Indonesia. Laporan Perkembangan HIV AIDS dan Penyakit Infeksi Menular Seksual (PIMS) Triwulan I Tahun 2021. Jakarta: Kementerian Kesehatan Republik Indonesia; 2022.
5. Fauk NK, Mwanri L, Hawke K, Mohammadi L, Ward PR. Psychological and social impact of HIV on women living with HIV and their families in low- and middle-income Asian countries: A systematic search and critical review. Int J Environ Res Public Health. 2022; 19 (11): 6668.
6. Fauk NK. Risk factors and the impact of HIV among women living with HIV and their families in Yogyakarta and Belu district, Indonesia [Dissertation]. Australia: Flinders University; 2022.
7. Akinboro AO, Akinyemi SO, Olaitan PB, Raji AA, Popoola AA, Awoyemi OR, et al. Quality of life of Nigerians living with human immunodeficiency virus. The Pan African Med J. 2014; 18: 234.
8. Monteiro F, Canavarro M, Pereira M. Factors associated with quality of life in middle-aged and older patients living with HIV. AIDS Care. 2016; 28 Suppl 1 (sup1): 92-8.
9. Karkashadze E, Gates MA, Chkhartishvili N, DeHovitz J, Tsertsvadze T. Assessment of quality of life in people living with HIV in Georgia. Int J STD AIDS. 2017; 28 (7): 672–8.
10. Osei-Yeboah J, Owiredu WKBA, Norgbe GK, Lokpo SY, Obirikorang C, Alote Allotey E, et al. Quality of life of people living with HIV/AIDS in the Ho municipality, Ghana: A cross-sectional study. AIDS Res Treat. 2017; 6806951.
11. Nigusso FT, Mavhandu-Mudzusi AH. Health-related quality of life of people living with HIV/AIDS: The role of social inequalities and disease-related factors. Health Qual Life Outcomes. 2021; 19: 63.
12. Seguiti C, Salvo PF, Di Stasio E, Lamonica S, Fedele AL, Manfrida S, et al. Health-related quality of life (HRQoL) from HIV patients’ perspective: Comparison of patient-reported outcome (PRO) measures among people living with hiv (PLWH) and other chronic clinical conditions. JPatient Rep Outcomes. 2022; 6: 27.
13. Khademi N, Zanganeh A, Saeidi S, Teimouri R, Khezeli M, Jamshidi B, et al. Quality of life of HIV-infected individuals: Insights from a study of patients in Kermanshah, Iran. BMC Infect Dis. 2021; 21: 203.
14. Hidru TH, Wang F, Lolokote S, Jia Y, Chen M, Tong W, et al. Associated factors of self-reported psychopathology and health related quality of life among men who have sex with men (MSM) with HIV/AIDS in Dalian, China: A pilot study. Infect Dis Poverty. 2016; 5: 108.
15. Song B, Yan C, Lin Y, Wang F, Wang L. Health-related quality of life in HIV-infected men who have sex with men in China: a cross-sectional study. Med Sci Monit. 2016; 22: 2859-70.
16. Nobre N, Pereira M, Roine RP, Sintonen H, Sutinen J. Factors associated with the quality of life of people living with HIV in Finland. AIDS Care. 2017; 29 (8): 1074–8.
17. Popping S, Kall M, Nichols BE, Stempher E, Versteegh L, van de Vijver DAMC, et al. Quality of life among people living with HIV in England and the Netherlands: A population-based study. Lancet Reg Heal - Eur. 2021; 8: 100177.
18. Desyani NLJ, Waluyo A, Yona S. The relationship between stigma, religiosity, and the quality of life of HIV-positive MSM in Medan, Indonesia. Enfermería Clínica. 2019; 29 (Suppl. 2): 510–4.
19. Gao C, Xiao X, Zhang L, Xu H, Wang M, Wang H. The relationship between acceptance of illness and quality of life among men who have sex with men living with human immunodeficiency virus: A cross-sectional study. Int J Nurs Sci. 2022; 9 (3): 313–20.
20. Martiana I, Waluyo A, Yona S, Edianto. Dukungan Sebaya dan Penerimaan Keluarga terhadap Kualitas Hidup Homoseksual dengan HIV dan Terapi Antiretroviral. J Kep Indones. 2021; 24 (1).
21. Putra INAM, Waluyo A, Yona S. The relationship between family acceptance and quality of life and self esteem of PLWH MSM in Medan, North Sumatera, Indonesia. Enfermería Clínica. 2019; 29 (Suppl. 2): 291-4.
22. Lwanga SK, Lemeshow S, & World Health Organization. Sample size determination in health studies: a practical manual / S. K. Lwanga and S. Lemeshow. Geneva: World Health Organization; 1991.
23. Muhammad NM, Shatri H, Djoerban Z, Abdullah M. Validity and readability test of Indonesian version of World Health Organization Quality of Life-HIV BREF Questionnaire to measure the quality of life patients with HIV/AIDS. J Penyakit Dalam Indonesia. 4 (3): 112-122.
24. Dar P, Kachroo V, Qureshi S. Prevalence of depression in HIV patients on antiretroviral therapy (ART). Int J Res Rev. 2020; 7 (4): 13-21.
25. Nurdin HC. Uji Validitas dan Reliabilitas Berger HIV Stigma Scale versi Bahasa Indonesia dalam menilai Perceived Stigma pada Orang dengan HIV/AIDS (ODHA). AIDS. 2013.
26. Arikunto S. Prosedur penelitian: suatu pendekatan praktik. Jakarta: Rineka Cipta; 2010.
27. Bhatia MS, Munjal S. Prevalence of depression in people living with HIV/AIDS undergoing art and factors associated with it. J Clin Diagn Res. 2014; 8 (10): WC01-4.
28. Rivera-Rivera Y, Vázquez-Santiago FJ, Albino E, Sánchez MDC, Rivera-Amill V. Impact of depression and inflammation on the progression of HIV disease. J Clin Cell Immunol. 2016; 7 (3): 423.
29. Lopresti AL, Hood SD, Drummond PD. A review of lifestyle factors that contribute to important pathways associated with major depression: diet, sleep and exercise. J Affect Disord. 2013; 148 (1): 12–27.
30. Mohammed M, Mengistie B, Dessie Y, Godana W. Prevalence of depression and associated factors among HIV patients seeking treatments in ART clinics at Harar Town, Eastern Ethiopia. J AIDS Clin Res. 2015; 6 (6): 474.
31. Fauk NK, Merry MS, Ambarwati A, Sigilipoe MA, Ernawati, Mwanri L.A qualitative inquiry of adherence to antiretroviral therapy and its associated factors: A study with transgender women living with HIV in Indonesia. Indian J Public Health. 2020; 64 (2): 116–23.
32. Bello SI, Bello IK. Quality of life of HIV/AIDS patients in a secondary health care facility, Ilorin, Nigeria. Proc (Bayl Univ Med Cent). 2013; 26 (2): 116–9.
33. Achappa B, Madi D, Bhaskaran U, Ramapuram JT, Rao S, MahalingamS. Adherence to antiretroviral therapy among people living with HIV. NAm J Med Sci. 2013; 5 (3): 220-3.
34. Fauk NK, Hawke K, Mwanri L, Ward PR. Stigma and discrimination towards people living with HIV in the context of families, communities, and healthcare settings: A qualitative study in Indonesia. Int J Environ Res Public Health. 2021; 18 (10): 5424.
35. Fauk NK, Ward PR, Hawke K, Mwanri L. HIV stigma and discrimination: perspectives and personal experiences of healthcare providers in Yogyakarta and Belu, Indonesia. Front Med. 2021; 8.
36. Mahamboro DB, Fauk NK, Ward PR, Merry MS, Siri TA, Mwanri L. HIV stigma and moral judgement: Qualitative exploration of the experiences of hiv stigma and discrimination among married men living with HIV in Yogyakarta. Int J Environ Res Public Health. 2020; 17 (2): 636.
37. Xu JF, Ming ZQ, Zhang YQ, Wang PC, Jing J, Cheng F. Family support, discrimination, and quality of life among ART-treated HIV-infected patients: A two-year study in China. Infect Dis Poverty. 2017; 6 (1): 152.
38. Kebede MA, Haidar J. Factors influencing adherence to the food by prescription program among adult HIV positive patients in Addis Ababa, Ethiopia: A facility-based, cross-sectional study. Infect Dis poverty. 2014; 3: 20.
39. Mugavero MJ, Amico KR, Horn T, Thompson MA. The state of engagement in HIV care in the United States: From cascade to continuum to control. Clin Infect Dis. 2013; 57 (8): 1164–71.
Recommended Citation
Sitorus RJ , Antara NY , Sangalang R ,
et al.
Understanding the Health-related Quality of Life of People Living with HIV Based on Sexual Orientation.
Kesmas.
2023;
18(1):
73-79
DOI: 10.21109/kesmas.v18i1.6623
Available at:
https://scholarhub.ui.ac.id/kesmas/vol18/iss1/10