Abstract
Introduction. Community acquired pneumonia (CAP) now is known as the most common infection presented. Empiric antibiotic administered followed by observing parameters. This study aimed to know how far the American Thoracic Society/ Infectious Disease Society of America (ATS/IDSA) antibiotic guidelines 2007 based treatment influenced the length of stay (LOS) of CAP subject in a private hospital ward between January 2014-August 2015 Methods. A retrospective cohort was conducted with bivariate analysis and multivariate analysis for reducing the confounding factor. Sample taken with proportional sampling formula at ward in a hospital in Jakarta. Results. The result showed that subjects with unproper empiric antibiotic based on ATS/IDSA 2007 guidelines tent to have hospital prolong stay 10.25 times (p <0.001) than others with proper on ATS/IDSA empiric antibiotic guidelines. Conclusion. By this result, we observed a very significant statistic result difference in LOS between a group with proper empiric antibiotic based on ATS/IDSA 2007 guidelines and other who unproper.
References
1. Kementerian Kesehatan Republik Indonesia. Profil kesehatan Indonesia 2016. Jakarta: Kementerian Keseharan Republik Indonesia; 2017. hal.163-5. 2. Chambers HF. Antimicrobial agents. In: Hardman JG, Limbird LE, GilmanAG, editors. Goodman and Gilman’s pharmacological basis of therapeutics. 10th ed. New York: McGrawHills; 2001. p.1143-70. 3. Setiawan B, Nainggolan L. Prinsip penggunaan antibiotika. Bunga rampai penyakit infeksi, edisi I. Jakarta: Divisi Tropik Infeksi, Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Indonesia; 2004. hal.104-15. 4. Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD, Dean NC, et al. Infectious diseases society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis. 2007;44(Suppl 2):S27-72. 5. Gold HS, Moellering RC. Antimicrobial drug resistance. N Engl J Med. 1996;335(19):1445-53. 6. Moran JG, Krishnadasan A, Gorwitz RJ, Fosheim GE, Carey RB, et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med. 2006;355(7):666-74. 7. Ariawan I. Besar dan metode sampel pada penelitian kesehatan. Depok: Jurusan Biostatistik Kependudukan Fakultas Kesehatan Masyarakat Universitas Indonesia; 1998. hal.37-8. 8. Sari EF, Rumende CM, Harimurti K, Faktor-faktor yang berhubungan dengan diagnosis pneumonia pada pasien usia lanjut. JPDI. 2016:3(4):181-93. 9. Welte T, Torres A, Nathwani D. Clinical and economic burden of community-acquired pneumonia among adults in Europe. Thorax. 2012;67(1):71-9. 10. Torres A, Peetermans WE, Viegi G, Blasi F. Risk factors for community-acquired pneumonia in adults in Europe: a literature review. Thorax. 2013;68(11):1057-65. 11. Dahlan S. Analisa multivariat regresi logistik. Seri 9. Jakarta: Sagung Seto; 2012. hal.95-107. 12. Ellen M, Baker R, Brown A. The impact of acute care clinical practice guidelines on length of stay. A closer look at some conflicting findings. J Hospital Administration. 2014;3(4):28-36. 13. Niederman MS, Mandell LA, Anzueto A, Bass JB, Broughton WA, Campbell GD, et al. Guidelines for management of adults with community – acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy, and prevention. Am J Respir Crit Care Med. 2001;163(7):1730-54. 14. Rotter T, Kinsman L, James EL, Machotta A, Gothe H, Willis J, et al. Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs. Cochrane Database Syst Rev. 2010;3:CD006632. 15. Kementerian Kesehatan Republik Indonesia. Pedoman umum penggunaan antibiotik. Jakarta: Direktorat Jenderal Bina Kefarmasian dan Alat Kesehatan; 2011. hal.6-77. 16. Peraturan Menteri Kesehatan Republik Indonesia Nomor 8 Tahun 2015. Pedoman Program Pengendalian Resistensi Antimikroba di Rumah Sakit. Jakarta: Kementerian Kesehatan Republik Indonesia; 2015. hal.1-32.
Recommended Citation
Munarsih, Fetri Charya; Natadidjadja, Ronald Irwanto; and Syamsudin, Syamsudin
(2018)
"Antibiotic Treatment based on Guidelines for Reducing Length of Stay (LOS) in Patients with Community Acquired Pneumonia (CAP),"
Jurnal Penyakit Dalam Indonesia: Vol. 5:
Iss.
3, Article 7.
DOI: 10.7454/jpdi.v5i3.195
Available at:
https://scholarhub.ui.ac.id/jpdi/vol5/iss3/7