Abstract
Introduction. Stigma and discrimination among HIV/AIDS patients cause varrious problems such as physical, psychological, and social. Therefore, its management requires comprehensive intervention. Antiretroviral therapy improves the patient’s clinical course, but may lead to neuropsychiatric complications especially anxiety disorders, depression, and psychotic disorders. This study aimed to know the associationbetween stigma,ARV therapy and complications of psychiatric disorders of HIV patients. Methods. A cross-sectional study was conducted among HIV/AIDS patients undergoing antiretroviral therapy in VCT-CST RSUP dr. Kariadi and RSUD RAA Soewondo Pati. Subjects were recruited using consecutive sampling method. Asessment of disorders and stigma was conducted using Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and Questionnaire scale perception of PLWHA on community HIV/AIDS stigma. Analysis was performed using SPSS program. Correlation test analyzed with chi square test. Results. Total of 102 subjects were included in this study. The majority of subjects was male (51%) and the age mean value was 35.88 (SD 8.24) years. The most common type of antiretroviral drugs bas lamividine+zidovudine) + nevirapine (52.9%). The highest stigma scale of PLHIV was 95.1% positive stigma. Characteristics of psychiatric disorders consisted of 89.2% experienced psychiatric disorders, most depression 30.4%, and 6.9% psychotic disorders. Analysis showed that there was a statistically significant association between type of ARV therapy and psychiatric disorder. There was no statistically significant association between stigma and psychiatric disorders. Conclusions. There is an association between type of ARV therapy andpsychiatric disorders, but no association found between stigma and psychiatric disorders
References
1. Goldenberg D, Boyle BA. HIV dan Psikiatri: Bagian 1. Jakarta: Yayasan Spiritia; 2000. hal.1-4. 2. Djoerban Z, Djauzi S. HIV/AIDS di Indonesia. Dalam: Setiati S, Alwi I, Sudoyo AW, Simadibrata M, Setiyohadi B, Syam AF, editors. Buku ajar ilmu penyakit dalam Ed Keenam Jilid I. Jakarta: Pusat Penerbitan Ilmu Penyakit Dalam; 2014. 3. Sofro MAU, Sujatmoko SA. Sehat dan Sukses dengan HIV-AIDS. Jakarta: Gramedia; 2015. 4. Nebhinani1 N, Mattoo SK. Psychotic disorders with HIV infection: A Review. German J Psychiatry. 2013;16(1):43-8. 5. Chandra PS, Desai G, Ranjan S. HIV and psychiatric disorders. India J Med Res. 2005;121:451-67. 6. Kementerian Kesehatan RI. Rencana Strategis Kementerian Kesehatan Tahun 2015-2019. Jakarta: Kementerian Kesehatan RI; 2015. 7. Robertson K, Liner J, Heaton R. Neuropsychological assessment of HIV-Infected populations in international settings. Neuropsychol Rev. 2009;19(2):232-49. 8. Gutierrez F, Navarro A, Padilla S, Antón R, Masiá M, Borrás J, et al. Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring. Clin Infect Dis. 2005;41(11):1648-53. 9. First MB, Gibbon M, Spitzer RL, Williams JBW. User’e guide for the SCID-I structured clinical interview for DSM-IV-TR axis i disorders (research version). New York: Biometrics Research Department; 2002. 228 p. 10. Watkins CC, Treisman GJ. Cognitive impairment in patients with AIDS – prevalence and severity. HIV/AIDS (Auckl). 2015;7:35-47. 11. Adejumo O, Oladeji B, Akpa O, Malee K, Baiyewu O, Ogunniyi A, et al. Psychiatric disorders and adherence to antiretroviral therapy among a population of HIV-infected adults in Nigeria. Int J STD AIDS. 2016;27(11):938–49. 12. American Psychiatric Association. HIV mental health treatment issue, HIV and anxiety. Arlington: American Psychiatric Association; 2012. 13. Fauci AS, Lane HC. Human immunodeficiency virus disease: AIDS and related disorders. In: Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson J, Loscalzo J, editors. Harrison’s principles of internal medicine 19th Ed. New York: McGraw-Hill; 2015. p.1215-85. 14. Mashaphu S, Mkize DL. HIV seropositivity in patients with first episode psychosis. S Afr J Psychiatr. 2007;13(3):90-4. 15. Gazzard B, Balkin A, Hill A. Analysis of neuropsychiatric adverse events during clinical trials of efavirenz in ART-naïve patients: a systematic review. AIDS Rev. 2010;12(2):67-75. 16. Djoerban Z, Djauzi S. HIV/AIDS di Indonesia. Dalam: Setiati S, Alwi I, Sudoyo AW, Simadibrata M, Setiyohadi B, Syam AF, editors. Buku ajar ilmu penyakit dalam jilid III 5th ed. Jakarta: Pusat Penerbit Ilmu Penyakit Dalam; 2009.
Recommended Citation
Wicaksono, Yamaji Adi; Fitrikasari, Alifiati; Sofro, Muchlis Achsan Udji; and Peni, Hari
(2018)
"Association between Stigma, ARV Therapy and Complications ofPsychiatric Disorders iIn HIV / AIDS Patients,"
Jurnal Penyakit Dalam Indonesia: Vol. 5:
Iss.
1, Article 5.
DOI: 10.7454/jpdi.v5i1.161
Available at:
https://scholarhub.ui.ac.id/jpdi/vol5/iss1/5
