Abstract
Severe Malaria is commonly found due to Plasmodium falciparum infection, which is causing high mortality in patient. A Severe case might be difficult to treat optimally in the remote settings area that could be due to lack in awareness of disease manifestation and inadequate diagnostic facilities. We report a case of Severe Malaria Falciparum infection, confirmed by blood smear examination of Plasmodium falciparum (Pf) parasites. Patient had received Artemicinin Based Combination Therapy (ACT), which consisted of dihydroartemisinin (DHA)-piperaquine and primaquine (PQ) with no clear clinical and microscopy improvement. The second line anti malaria consisted of quinine, doxycycline, and PQ was then initiated, showing clinical and microscopy responses.
References
1. Ditjen Pengendalian Penyakit dan Penyehatan Lingkungan Kementerian Kesehatan RI. Buku saku penatalaksanaan kasus malaria. Jakarta: Kementerian kesehatan Republik Indonesia; 2012. h.1-37. 2. Whyte IM. Antimalarial agents. Dalam: Caravati EM, McGuigan MA, Whyte IM, Dawson AH, Seifert Sam Schinwald S. Medical toxicology. Edisi ke-3. Philadelphia: Lippincott Williams & Wilkins; 2014. p.466-74 3. World Health Organization. Global report on antimalarial drug efficacy and drug resistance: 2000-2010. Switzerland: WHO; 2010. p.9-26. 4. Cheng Q, Kyle DE, Gatton ML. Artemisinin resistance in plasmodium falciparum: a process linked to dormancy? Int J Parasitol. 2012;2:249-55. 5. Ashley EA, Dhorda M, Fairhust RM, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in plasmodium falciparum malaria. N Engl J Med. 2014;371(5):411-23. 6. Gueye CS, Newby G, Hwang J, Phillips AA, Whittaker M, MacArthur JR, et al. The challenge of arteminisin resistance can only be met by eliminating plasmodium falciparum malaria across the greater mekong subregion. Malar J. 2014;13(1):286.
Recommended Citation
Priantono, Dimas; Purnama, Asep; and Nelwan, Erni Juwita
(2017)
"Challenges in Providing Treatment of Severe Malaria Case in aDistrict Hospital of Remote Area in Indonesia,"
Jurnal Penyakit Dalam Indonesia: Vol. 4:
Iss.
1, Article 8.
DOI: 10.7454/jpdi.v4i1.112
Available at:
https://scholarhub.ui.ac.id/jpdi/vol4/iss1/8