Abstract
Introduction. Helicobacter pylori (H. pylori) infection risk is associated with many factors related to host-agent-environment. Ethnicity is one of the host factors which was the most studied factor overseas. The prevalence of H. pylori infection was found higher in certain ethnic such among Chinese. Based on migration and transmission theory, it was suspected that H. pylori infection was transmitted by people migrating from areas with a high prevalence of infection to the destination area. Chinese in West Borneo are originated from South China region where the prevalence of H. pylori infection is high. It is estimated that there are differences in the prevalence of H. pylori infection among Chinese compared to the native people of West Borneo, the Dayaknese. Methods. This was a cross-sectional study to determine the differences in the prevalence of H. pylori infection. The study was conducted at St. Antonius General Hospital Pontianak from December 2014 to June 2015 with consecutive sampling method. H. pylori infection prevalence is presented in percentage numbers, while the epidemiological characteristics and endoscopic finding differences among Chinese and Dayaknese were analyzed by bivariate analysis using the chi-square with significance value (p) = 0.05. Results. From a total of 203 subjects in this study, consisted of 102 Chinese subjects and 101 Dayaknese subjects, the prevalence of H. pylori infection was 40.8%. The prevalence among Chinese is higher than Dayaknese, which is 48.0% and 33.7%, respectively. There is no difference in the epidemiological characteristics and endoscopic findings in both ethnic groups. Conclusions. The prevalence of H. pylori infection among the Chinese (48.0%) is higher than among Dayaknese (33.7%). There is no difference in the epidemiological characteristics and endoscopic findings among both ethnic groups.
References
1. Huether SE. Alterations of digestive function. In: McCance KL, Huether SE, Brashers VL, Rote NS, editors. Pathophysiology:the biologic basis for disease in adults and children, 6th ed. Missouri: Elsevier; 2010. p1452-515. 2. Bauer B, Meyer TF. The human gastric pathogen Helicobacter pylori and its association with gastric cancer and ulcer disease. Ulcers J. 2011;20(11):2001-23 3. Shi Y, Gong H, Zhou L, Shi Y, Cao W, Cheng L. Association between Helicobacter pylori Infection and Laryngeal Squamous Cell Carcinoma in a Chinese Male Population. ORL J Otorhinolaryngol Relat Spec. 2011;73(6):295-300. 4. Kusters JG, Vliet AHM, Kuipers EJ. Pathogenesis of Helicobacter pylori infection. Clin Microbiol Rev. 2006;19(3):449–90. 5. Perkumpulan Gastroenterologi Indonesia (PGI) dan Kelompok Studi Helicobacter pylori Indonesia (KSHPI). Konsensus nasional penatalaksanaan dispepsia dan infeksi Helicobacter pylori. KM Simadibrata, Mskmun D, Abdullah M, Syam AF, Fauzi A, Renaldi K, Maulahela H, Utari AP, editor. Jakarta: PGI KSHPI; 2014. 6. Sujendera AK. Epidemiologi Infeksi Helicobacter pylori pada orang dewasa di Desa Antap Kecamatan Selemadeg Kabupaten Tabanan (Tesis). Denpasar: Fakultas Kedokteran Universitas Udayana; 2004. 7. Vale FF, Vítor JMB. Transmission pathway of Helicobacter pylori: does food play a role in rural and urban areas? Int J Food Microbiol. 2010;138(1-2):1-12. 8. Sasidharan S, Lachumy SJT, Ravichandran M, Latha LY, Gegu SRS. Epidemiology of Helicobacter pylori among multiracial community in Nothern Peninsular, Malaysia: effect of age across race gender. APJTM. 2011;4(1):72-5 9. Goh KL, Parasakthi N. The racial cohort phenomenon: seroepidemiology of Helicobacter pylori infection in a multiracial South-East Asian country. Eur J Gastroenterol Hepatol. 2000;13:177-83. 10. Zajacova A, Dowd JB, Aiello AE. Socioeconomic and race/ethnic patterns in persistent infection burden among U.S. adults. J Gerontol A Biol Sci Med Sci. 2009;64A(2):272–9. 11. Khalifa MM, Sharaf RR, Aziz RK. Helicobacter pylori: a poor man’s gut pathogen? Gut Pathog. 2010;2(1):1-12. 12. World Gastroenterology Organisation. World Gastroenterology Organisation Global Guideline: Helicobacter pylori in Developing Countries. J Clin Gastroenterol. 2011;45(5):383-8. 13. Soeripto, Indrawati, Indrayanti. Gastro-intestinal Cancer in Indonesia. Asian Pac J Cancer Prev. 2003;4(4):289-96. 14. Simadibrata M, Yuwono V, Rani AA. Helicobacter pylori in Gastric Cancer. J Gastroenterol Hepatol.2000;15(12):H4. 15. Akil M. Fenomena Etnisitas di Kalimantan Barat. Dalam: Florus F, Djuweng S, Bamba J, Andasputra N, editor. Kebudayaan Dayak: Aktualisasi dan Transformasi. Jakarta: Grasindo, 1994.p.183-98. 16. MacKinnon K, Hatta G, Halim H, Mangalik A. Sejarah Manusia di Borneo. Dalam: Kartikasari SN (editor seri) Ekologi Kalimantan: Seri Ekologi Indonesia. Buku III. Jakarta: Prenhallindo; 2000.p.54-65. 17. Fock KM, Ang TL. Epidemiology of Helicobacter pylori Infection and gastric cancer in Asia. J Gastroenterol Hepatol. 2010;25(3):479-86. 18. Wroblewski LE, Peek RM, Wilson KT. Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev. 2010;23(4):713–39. 19. Fock KM, Katelaris P, Sugano K, Tiing LA, Hunt L, Talley NJ,et al. Second Asia-Pacific Consensus Guidelines for Helicobacter pylori infection. J Gastroentereol Hepatol. 2009;24(10):1587-600. 20. Soertato E, Sitorus MTF, Napiri MY. Decentralisation of Administration, Policy Making and Forest Management in Ketapang District, West Kalimantan. Jakarta: Center for International Forestry Research, 2001. p.1. 21. Arrosy, Ratnasari N, Indarti F. Abstract: Prevalence of Helicobacter pylori infection based on histopathology of gaster and duodenum in Dr. Sardjito Hospital, Yogyakarta September 2009–September 2010. Yogyakarta; 2012. 22. McColl KE, Omar EE, Gillen D. Interactions between H.Pylori infection, gastric acid secretion and anti secretory therapy. Br Med Bull. 1998;54(1):121-38. 23. Rani AA, Fauzi A. Infeksi Helicobacter pylori dan penyakit g astroduodenal. Dalam: Sudoyo AW, Setyohadi B, Alwi I, Simandibrata M, Setiati S, editor. Buku Ajar Penyakit Dalam Jilid 1. Jakarta: Pusat Penerbit Ilmu Penyakit Dalam FKUI, 2006. p.331-36. 24. Saragih JB, Akbar N, Syam AF, Sirait S, Himawan S, Soetjahyo E. Incidence of Helicobacter pylori infection and gastric cancer : an 8-year hospital based study. Acta Med Indones J intern Med. 2007;39(2):79-81. 25. Borg J, Melander O, Johansson L, Moberg K, Rehfeld JF, Ohlsson B. Gastroparesis is associated with oxytocin deficiency, oesophageal dysmotility with hypercalcemia, and autonomic neuropathy with hypergastrinemia. BMC Gastroenterol. 2009;9(17):1-9. 26. Beevers DG, Lip GY, Blann AD. Salt Intake and Helicobacter pylori Infection. J Hypertens. 2004;22(8):1475-7. 27. Aguemon BD, Struelens MJ, Massougbodji A, Ouendo EM. Prevalence and risk-factors for Helicobacter pylori infection in urban and rural Beninese populations. Clin Microbiol Infect. 2005;11(8):611–7. 28. Lee YY, Ismail AW, Mustaffa N, Musa KI, Majid NA, Choo KE. Sociocultural and Dietary Practices Among Malay Subjects in the North-Eastern Region of Peninsular Malaysia: A Region of low Prevalence of Helicobacter pylori infection. Helicobacter. 2011;17(1):54-61. 29. Brenner H, Rothenbacher D, Bode G, Adler G. Relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection: cross sectional study. BMJ. 1997;315(7121):1489–92. 30. Ghosh P, Kandhare AD, Raygude KS, Gauba D, Gosavi TP, Bodhankar SL. Cigarette smoking and H.pylori infection: A meta-analysis of literature. Der Pharmacia Lettre. 2012;4(1):128-34. 31. Tsugane S. Salt, salted food intake, and risk of gastric cancer: epidemiologic evidence. Cancer Sci. 2005;96(1):1–6. 32. Robert A, Nezamis JE, Lancaster C, Davis JP, Field SO, Hanchar AJ. Mild irritants prevent gastric necrosis through “adaptive cytoprotection” mediated by prostaglandins. Am J Physiol. 1983;245(1):G113–21. 33. Weisse ME, Eberly B, Person DA. Wine as a digestive aid: comparative antimicrobial effects of bismuth salicylate and red and white wine. BMJ. 1995;311(7021):1657–60. 34. Dorji D, Dendup T, Malaty HM, Wangchuk K, Yangzom D, Richter JM. Epidemiology of Helicobacter pylori in Bhutan: The Role of Environment and Geographic Location. Helicobacter. 2013;19(1):69-73. 35. Abahussain EA, Hasan FAM, Nicholls PJ. Dyspepsia and Helicobacter pylori infection: Analysis of 200 Kuwaiti patients referred for endoscopy. Ann Saudi Med. 1998;18(7):502-5.
Recommended Citation
Uwan, Willy Brodus; Syam, Ari Fahrial; Lesmana, C. Rinaldi A.; and Rumende, C Martin
(2016)
"The Difference in Prevalence of Helicobacter pylori Infectionbetween Chinese and Dayak Ethnics with Dyspepsia Syndrome,"
Jurnal Penyakit Dalam Indonesia: Vol. 3:
Iss.
1, Article 6.
DOI: 10.7454/jpdi.v3i1.5
Available at:
https://scholarhub.ui.ac.id/jpdi/vol3/iss1/6