Abstract
Introduction. The Get with the Guidelines-Heart Failure (GWTG-HF) risk score is a widely utilized and validated tool for assessing prognosis in patients with heart failure. Inflammation significantly contributes to the pathophysiology of heart failure, evidenced by platelet activation and a reduction in lymphocyte counts. Consequently, the platelet-to-lymphocyte ratio (PLR) may function as a prognostic biomarker in this population. This study aims to investigate the correlation between the GWTG-HF risk score and PLR as an inflammatory marker in patients hospitalized with heart failure.
Methods. This cross-sectional study utilized medical records of heart failure patients admitted to Adam Malik Hospital in Medan from January 2022 to July 2023. Total GWTG-HF scores and PLR values were recorded at the time of patient admission. Correlation analyses were conducted to assess the relationship between the two variables.
Results. The study evaluated 106 patient records, with male patients comprising 72.64% and a mean age of 55.84 (SD 14.09) years. The median GWTG-HF score was 37.5, while the median PLR was 137.14. Correlation analysis yielded a coefficient of r = 0.249 (p < 0.05), indicating a statistically significant association.
Conclusion. A weak positive correlation exists between the GWTG-HF score and PLR in patients with heart failure, suggesting that PLR may serve as a supplementary inflammatory marker in prognostic assessments.
Bahasa Abstract
Pendahuluan. Get with the guidelines-heart failure (GWTG-HF) merupakan salah satu sistem skor yang umum digunakan dan tervalidasi dalam menilai prognosis pada pasien gagal jantung. Inflamasi mempunyai peran penting dalam patofisiologi gagal jantung dimana terjadi aktivasi trombosit dan penurunan jumlah limfosit. Oleh karena itu, Rasio Platelet Limfosit (RPL) memiliki potensi sebagai prediktor luaran pada pasien gagal jantung. Penelitian ini bertujuan untuk mengetahui apakah terdapat korelasi antara skor risiko GWTG-HF dengan RPL pada pasien rawat inap dengan gagal jantung.
Metode. Studi potong lintang dilakukan dengan menggunakan data rekam medis pasien gagal jantung yang dirawat inap di Rumah Sakit Adam Malik Medan antara Januari 2022 sampai Juli 2023. Dilakukan pencatatan total skor GWTG-HF dan nilai RPL saat pasien masuk rumah sakit. Uji korelasi digunakan untuk menilai hubungan diantara kedua variabel.
Hasil. Terdapat 106 data pasien dalam penelitian ini dan mayoritas pria (72,64%) dengan rerata usia 55,84 (SB 14,09) tahun. Median skor GWTG-HF 37,5 dan median nilai RPL 137,14. Hasil uji korelasi menunjukkan nilai koefisien korelasi r=0,23 (p<0,05).
Kesimpulan. Terdapat korelasi positif lemah antara skor GWTG-HF dengan nilai RPL.
Kata Kunci: Gagal jantung, rasio platelet limfosit, skor GWTG-HF
Recommended Citation
Panjaitan, Samuel Hendryk; Dalimunthe, Naomi Niari; Supriatmo, Supriatmo; and Pradana, Andika
(2024)
"Korelasi Skor Get with The Guidelines-Heart Failure dan Rasio Platelet Limfosit pada Pasien Rawat Inap dengan Gagal Jantung,"
Jurnal Penyakit Dalam Indonesia: Vol. 11:
Iss.
3, Article 1.
DOI: 10.7454/jpdi.v11i3.1539
Available at:
https://scholarhub.ui.ac.id/jpdi/vol11/iss3/1