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Psychological Distress and Quality of Life Among Infertility Couples Undergoing Infertility Treatment in Malaysia

Abstract

Infertility often leads to stress, anxiety, and depression, significantly affecting the quality of life of affected couples. This study explored the sociodemographic and psychological factors influencing the quality of life among infertile couples undergoing in vitro fertilization (IVF) treatment in Malaysia, using a cross-sectional design. A total of 126 infertile couples were purposively sampled from three public hospitals offering IVF treatment. The Depression, Anxiety, and Stress Scale (DASS-21) measured psychological distress levels, while the Fertility Quality of Life (Ferti-QoL) scale assessed fertility-related quality of life. Data collection adhered to strict ethical standards, with confidentiality ensured. Participants provided informed consent and completed surveys independently in private settings to ensure unbiased responses. Statistical analyses, including t-tests, chi-square tests, and multiple linear regression, were employed to identify significant patterns and predictors. Results revealed that wives had significantly lower FertiQoL scores compared to husbands (p < 0.001). Wives also experienced higher levels of stress, anxiety, and depression as indicated by DASS-21 scores (p < 0.001). Regression analysis identified stress (p < 0.001), anxiety (p = 0.04), depression (p < 0.001), and gender (p = 0.02) as significant predictors of quality of life. Elevated levels of psychological distress were associated with a notable decline in quality of life, particularly among wives. These findings emphasize the importance of addressing mental health needs among couples undergoing IVF. Healthcare providers should focus on emotional preparedness and develop targeted strategies to reduce psychological distress, ultimately enhancing the overall quality of life during treatment.

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