•  
  •  
 

Abstract

Peripheral ameloblastoma (PA), an uncommon and unique form of odontogenic tumor, accounts for around 2-10% of all ameloblastomas. The extraosseous position is the distinguishing aspect of this form of tumor, which is otherwise comparable to a typical ameloblastoma. As late recurrence is also recorded, continuous follow-up is required. A case of peripheral ameloblastoma in a 23-year-old male that affected the right posterior palatal mucosa was presented in this case study. A 23-year-old male patient had an exophytic mass located at the junction of the hard and soft palate, in the palatal neighborhood of the tooth number 18. An excisional biopsy of the lesion was performed under local anesthesia, and the final diagnosis showed peripheral ameloblastoma. An appointment for intermittent controls was scheduled in case of a recurrence. PA arises at a much younger age than intraosseous ameloblastoma. It is an exophytic growth in the soft tissues overlaying the tooth-bearing portions of the jaws, with fibrous epulis being the most common first diagnosis. Conservative supraperiosteal surgical excision with appropriate disease-free margins is the current therapy of choice.

References

1. Yuwanati MB, Singh A, Gadbail AR, Mhaske S. Hybrid peripheral ameloblastoma of cheek mucosa. BMJ Case Rep. 2013; 2013:bcr2013009510.

2. Wettan HL, Patella PA, Freedman PD. Peripheral ameloblastoma: Review of the literature and report of recurrence as severe dysplasia. J Oral Maxillofac Surg. 2001; 59(7):811-5.

3. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO classification of head and neck tumours. Lyon: International Agency for Research on Cancer; 2022.

4. LeCorn DW, Bhattacharyya I, Vertucci FJ. Peripheral ameloblastoma: A case report and review of the literature. J Endod. 2006; 32(2):152-4.

5. Siar CH, Ng KH, Ngui CH, Chuah CH. Atypical peripheral ameloblastoma of the palate. J Laryngol Otol. 1990; 104(3):252-4.

6. Pekiner FN, Ozbayrak S, Sener BC, Olgaç V, Sinanoğlu A. Peripheral ameloblastoma: A case report. Dentomaxillofac Radiol. 2007; 36(3):183-6.

7. Ülker E , K irtiloğlu T , T aban B . P eripheral ameloblastoma: A case report. J Clin Exp Dent. 2020; 12(6):e607-9.

8. Pakhira S, Raha A, Mazumder P. Application of diode laser in excision of a peripheral ameloblastoma - A case report. Ann Maxillofac Surg. 2022; 12(2):252-5.

9. Singh R, Shrestha S, Acharya P, Shrestha A. Peripheral ameloblastoma of acanthomatous variant: A case report. JNMA J Nepal Med Assoc. 2022; 60(256):1045-8.

10. Vezhavendhan N, Vidyalakshmi S, Muthukumaran R, Santhadevy A, Sivaramakrishnan M, Gayathri C. Peripheral ameloblastoma of the gingiva. Autops Case Rep. 2019; 10(1):e2019127.

11. Ide F, Ito Y, Miyazaki Y, Nishimura M, Kusama K, Kikuchi K. A new look at the history of peripheral ameloblastoma. Head Neck Pathol. 2020; 14(4):1052-7.

12. Goda H, Nakashiro K, Ogawa I, Takata T, Hamakawa H. Peripheral ameloblastoma with histologically low-grade malignant features of the buccal mucosa: A case report with immunohistochemical study and genetic analysis. Int J Clin Exp Pathol. 2015; 8(2):2085-9.

13. Soluk-Tekkeşin M, Wright JM. The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017 (4th) Edition. Turk Patoloji Derg. 2018; 34(1):01410.

14. Surya V, Verma P, Amale K, Siwach P. A case of peripheral ameloblastoma of retromolar trigone: Histopathological and immunohistochemical profile. Contemp Clin Dent. 2015; 6(4):564-6.

15. Zhang X, Tian X, Hu Y, Zhang C, Wei C, Yang X. Oral peripheral ameloblastoma: A retrospective series study of 25 cases. Med Oral Patol Oral Cir Bucal. 2018; 23(3):e277-81.

16. Stanley HR Jr, K rogh HW. Per ipheral ameloblastoma; report of a case. Oral Surg Oral Med Oral Pathol. 1959; 12(6):760-5.

17. Al-Rawi NH, Othman S, Samsudin AR. Peripheral ameloblastoma of upper gingiva in a patient with port-wine stain. Case Rep Med. 2020; 2020:2870715.

18. Bertossi D, Favero V, Albanese M, De-Santis D, Martano M, Padovano-di-Leva A, De-Florio I, Nocini PF, Lo-Muzio L. Peripheral ameloblastoma of the upper gingiva: Report of a case and literature review. J Clin Exp Dent. 2014; 6(2):e180-4.

19. Nalin AS, Jayakrishnan R, Ziadeen S, Ameena M, Naziya NJ. Peripheral ameloblastoma – A unique presentation. IOSR J Dent Med Sci. 2016; 15(1):81- 5.

20. Philipsen HP, Reichart PA, Nikai H, Takata T, Kudo Y. Peripheral ameloblastoma: biological profile based on 160 cases from the literature. Oral Oncol. 2001; 37(1):17-27.

21. Beena VT, Choudhary K, Heera R, Rajeev R, Sivakumar R, Vidhyadharan K. Peripheral ameloblastoma: A case report and review of literature. Case Rep Dent. 2012; 2012:571509.

22. Premalatha BR, Patil S, Rao RS, Reddy NP, Indu M. Odontogenic tumor markers - an overview. J Int Oral Health. 2013; 5(2):59-69.

23. Kaneko T, Nakamura S, Kawano R, Horie N, Shimoyama T. Peripheral ameloblastoma of the mandible: a case report. J Oral Maxillofac Surg Med Pathol. 2016; 28(6):565-8.

24. Ghai S. Ameloblastoma: An updated narrative review of an enigmatic tumor. Cureus. 2022; 14(8):e27734.

25. Niccoli-Filho W, Gomes Mda G, Raldi FV, Seraidarian PI. Peripheral ameloblastoma. J Nihon Univ Sch Dent. 1997; 39(1):34-7.

26. Anpalagan A, Tzortzis A, Twigg J, Wotherspoon R, Chengot P, Kanatas A. Current practice in the management of peripheral ameloblastoma: A structured review. Br J Oral Maxillofac Surg. 2021; 59(1):e1-8.

27. Ide F, Kusama K, Tanaka A, Sakashita H. Peripheral ameloblastoma is not a hamartoma but rather more of a neoplasm. Oral Oncol. 2002; 38(3):318-20.

28. de Assis EM, Gomes HE, de Sousa FEM, Brener S, Leal RM, Souza PEA, Horta MCR. Recurrent peripheral ameloblastoma in an elderly patient: A case report. Gerodontology. 2019; 36(1):78-81.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.