Localized gingival overgrowths (LGOs) are relatively common clinical findings. These lesions can be associated with chronic irritation, infections, or they can represent benign or malignant tumors that can either be primary or metastatic. The etiology of these lesions is multifactorial, but the most prevalent cause is reactive hyperplasia and inflammation induced by dental plaque. Objective: This study presents the prevalence of LGOs in Northeast Thailand and identifies the most common LGOs in the region. Methods: A series of 218 LGO cases was studied. Results: Pyogenic granuloma (PG), gingival squamous cell carcinoma (GSCC), and peripheral ossifying fibroma (POF) were the three most common LGOs in this study. There were also interesting cases of soft tissue counterparts of benign odontogenic tumors and metastatic carcinomas to the gingiva with no evidence of bone invasion observed. Conclusion: The three most common LGOs in Northeast Thailand were PG, GSCC, and POF. This study provides baseline data on the prevalence of LGOs in Northeast Thailand.


1. Savage NW, Daly CG. Gingival enlargements and localized gingival overgrowths. Aust Dent J. 2010;55 Suppl 1:55–60.

2. Raizada S, Varghese JM, Bhat KM, Gupta K. Isolated gingival overgrowths: A review of case series. Contemp Clin Dent. 2016;7(2):265–8.

3. Rossman, JA. Reactive lesions of the gingiva: diagnosis and treatment options. The Open Pathol J. 2011;5:23-32.

4. Pushpalatha G, Shivakumar M, Mathew M, Suvarchala D. Gingival hyperplasia and quality of life. J Res Med Dent Sci. 2016;4(1):75-8.

5. Ozener HO, Kundak K, Sipahi NG, Yetis E, Dogan B. Different treatment approaches for the localized gingival overgrowths: Case series. Eur J Dent. 2018;12(2):311–6.

6. Agrawal AA. Gingival enlargements: Differential diagnosis and review of literature. World J Clin Cases. 2015;3(9):779–88.

7. Al-Rawi NH. Localized reactive hyperplastic lesions of the gingiva: a clinics-pathological study of 636 lesions form Iraq. Mustansiria Dent J. 2008;5(2):213-8.

8. Effiom OA, Adeyemo WL, Soyele OO. Focal Reactive lesions of the Gingiva: An Analysis of 314 cases at a tertiary Health Institution in Nigeria. Niger Med J. 2011;52(1):35–40.

9. Ramesh R, Sadasivan A. Oral squamous cell carcinoma masquerading as gingival overgrowth. Eur J Dent. 2017;11(3):390–4.

10. Walvekar A, Pai J, Gangamma G, Raju S, Sreedhar A, Uthappa M A. Gingival squamous cell carcinoma. J Int Clin Dent Res Organ 2017;9:94-8.

11. Parajuli R, Maharjan S. Unusual presentation of oral pyogenic granulomas: a review of two cases. Clin Case Rep. 2018;6(4):690–3.

12. Kfir Y, Buchner A, Hansen LS. Reactive lesions of the gingiva. A clinicopathological study of 741 cases. J Periodontol. 1980;51(11):655–61.

13. Angelopoulos AP. Pyogenic granuloma of the oral cavity: statistical analysis of its clinical features. J Oral Surg. 1971;29(12):840–7.

14. Buchner A, Calderon S, Ramon Y. Localized hyper plast ic lesions of the gingiva: a clinicopathological study of 302 lesions. J Periodontol. 1977;48(2):101–4.

15. Vilmann A , V ilmann P, V ilmann H . P yogenic granuloma: evaluation of oral conditions. Br J Oral Maxillofac Surg. 1986;24(5):376–82.

16. Nuyen BA, Tang CG. Gingival Metastasis: A Case Report and Literature Review. Perm J. 2016;20(1):71–3.


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