"Factors Associated With Neonatal Asphyxia" by Husnul Khotimah, Yosi Yusrotul Khasanah et al.
  •  
  •  
 

Abstract

Asphyxia in newborns is a common and serious cause of neonatal morbidity and mortality nationally and internationally. Risk factors for asphyxia can be seen from maternal and infant factors. The purpose of this study was to determine the risk factors in mothers and infants and to analyze which factors have the most influence on asphyxia. This study is a quantitative analytical study with a case-control approach. The number of case samples was 53 infants who experienced asphyxia and 53 control (1:1) infants so that the total sample was 106 infants. The variables studied were parity, Low Birth Weight (LBW), preeclampsia, and Premature Rupture of Membranes (PROM). Bivariate data analysis used chi square and multivariate data analysis used multiple logistic regression. The association value measured was the adjusted odds ratio (AOR), where AOR> 1 was interpreted as a risk. An increased risk was found in parity 1 and > 4 (AOR 3.824; 95% CI 1.220-11.994), LBW (AOR 11.726; 95% CI 3.282-41.898), preeclampsia (AOR 24.498; 95% CI 5.604-107.098), and PROM (AOR 18.821; 95% CI 4.377-80.928) with neonatal asphyxia. The dominant factor influencing neonatal asphyxia was preeclampsia with a value of 24.498 (AOR 24.498; 95%CI; 5.604-107.098), meaning that infants with a history of maternal preeclampsia had a 24 times greater chance of experiencing neonatal asphyxia compared to those without preeclampsia. There is an urgent need to develop strategies for early identification and management of birth asphyxia involving beneficiaries, health professionals and policy makers. Health workers should be trained to perform emergency obstetric care especially management of preeclampsia, LBW, PROM.

References

1. Lestari DL. Asfiksia Neonatorum. Sci J. 2024;3(1):8–15.

2. Wardlaw T, You D, Hug L, Amouzou A, Newby H. UNICEF Report: enormous progress in child survival but greater focus on newborns urgently needed. Reprod Health. 2014;11:1–4.

3. Committee WHOGA by the GR. Guidelines on basic newborn resuscitation. Geneva World Heal Organ. 2012;

4. Kemenkes RI. Kemenkes Ri. Profil Kesehat Indones. 2023;

5. Profil Kesehatan Dinas Kesehatan Provinsi Banten [Internet]. 2021. Available from: https://dinkes.bantenprov.go.id/storage/dinkes/files/1109/Profil Kesehatan/Profil Kesehatan Banten Tahun 2021.pdf

6. Kiyani AN, Khushdil A, Ehsan A. Perinatal factors leading to birth asphyxia among term newborns in a tertiary care hospital. Iran J Pediatr. 2014;24(5):637.

7. Antonucci R, Porcella A, Pilloni MD. Perinatal asphyxia in the term newborn. J Pediatr Neonatal Individ Med. 2014;3(2):e030269–e030269.

8. Serang RDP. Buku Register Ruang Perinatologi. 2020.

9. Anjani SM. Dampak Asuhan Berkelanjutan pada Ibu Hamil terhadap Kematian Neonatus di Perkotaan dan Pedesaan: Analisis Demographic and Health Surveys Indonesia 2017. J Epidemiol Kesehat Indones. 2023;7(2):9.

10. Organization WH. Trends in maternal mortality 2000 to 2020: estimates by WHO, UNICEF, UNFPA, World Bank Group and UNDESA/Population Division. World Health Organization; 2023.

11. Mongdong VAWM, Suryadinata RV, Boengas S, Saroh SA. Studi Faktor Risiko Preeklamsi terhadap Kejadian Asfiksia Neonatorum di RSUD dr. Sayidiman Magetan Tahun 2018. J Ilm Kedokt Wijaya Kusuma. 2021;10(1):11–9.

12. Setiyaningrum S. Buku Ajar Kegawatdaruratan Maternitas pada Ibu Hamil, Bersalin, Nifas. Indomedia Pustaka, Yogyakarta. 2017;

13. Rayuna MS, Andini HY, Virosi D. Hubungan Preeklamsia Berat (PEB) Dengan Kejadian Asfiksia Neonatorum Di RSUD Kelas B Kabupaten Subang Tahun 2019. J Ilm JKA (Jurnal Kesehat Aeromedika). 2020;6(2):33–40.

14. Gizachew S, Wogie G, Getnet M, Lonsako AA. Magnitude of neonatal asphyxia and its predictors among newborns at public hospitals of Wolaita Zone in Southern Ethiopia, 2023. BMC Pediatr. 2024;24(1):142.

15. Bedie NA, Wodajo LT, Mengesha ST. Magnitude and determinants of birth asphyxia: unmatched case control study Assela Referral Teaching Hospital, Arsi Zone, Ethiopia. Glob J Reprod Med. 2019;7(1):5556705.

16. Admasu FT, Melese BD, Amare TJ, Zewude EA, Denku CY, Dejenie TA. The magnitude of neonatal asphyxia and its associated factors among newborns in public hospitals of North Gondar Zone, Northwest Ethiopia: A cross-sectional study. PLoS One. 2022;17(3):e0264816.

17. Dashe JS, Bloom SL, Spong CY, Hoffman BL. Williams obstetrics. McGraw Hill Professional; 2018.

18. Cunningham FG, Leveno KJ, Bloom SL, Spong CY, Dashe JS, Hoffman BL, et al. Williams obstetrics. Vol. 7. McGraw-Hill Medical New York; 2014.

19. Wahyuningtiyas D. FAKTOR RISIKO TERJADINYA ASFIKSIA NEONATORUM PADA BAYI BARU LAHIR. J Borneo Holist Heal. 2023;6(1).

20. Wulandari P, Arifianto A, Senjani FP. Faktor–Faktor Yang Berhubungan Dengan Kejadian Asfiksia Neonatorum Di Ruang Melati RSUD Dr. h. soewondo Kendal. J Holist Nurs Sci. 2016;3(1):1–10.

21. Nurjayanti PD, Tyastuti S. Hubungan Paritas dan Umur Kehamilan dengan Kejadian Asfiksia pada Bayi Baru Lahir di RSUD Wonosari tahun 2016. Poltekkes Kemenkes Yogyakarta; 2018.

22. Vina E. HubunganParitas Dan Berat Bayi Lahir Dengan Kejadian Asfiksia Neonatorum Pada Bayi Baru Lahir. J Muara Sains, Teknol Kedokteran, dan Ilmu Kesehat. 2019;3(1):183–92.

23. Kleinbaum DG, Klein M, Kleinbaum DG, Klein M. Modeling strategy guidelines. Logist Regres A self-learning text. 2010;165–202.

Bahasa Abstract

Asfiksia pada bayi baru lahir merupakan penyebab morbiditas dan mortalitas neonatal yang umum dan serius secara nasional dan internasional. Faktor risiko penyebab asfiksia bisa dilihat dari faktor ibu dan bayi. Tujuan penelitian ini adalah untuk mengetahui faktor risiko pada ibu dan bayi serta menganalisis faktor mana yang paling berpengaruh terhadap asfiksia. Penelitian ini merupakan analitik kuantitatif dengan pendekatan case control.. Jumlah sampel kasus sebanyak 53 bayi yang mengalami asfiksia dan kontrol (1:1) sebanyak 53 bayi sehingga total sampel sebanyak 106 bayi. variabel yang diteliti adalah paritas, Berat Badan Lahir Rendah (BBLR), preeklamsia, dan Ketuban Pecah Dini (KPD). Analisis data bivariat menggunakan chi square dan multivariat menggunakan regresi logistik berganda. Nilai asosiasi yang diukur adalah adjusted odd ratio (AOR), di mana AOR >1 diinterpretasikan sebagai risiko. Ditemukan peningkatan risiko pada paritas 1 dan > 4 (AOR 3,824; 95% CI 1,220-11,994), BBLR (AOR 11,726; 95% CI 3,282-41,898), preeklamsia (AOR 24,498; 95% CI 5,604-107,098), dan KPD (AOR 18,821; 95% CI 4,377-80,928) dengan asfiksia neonatus. Faktor dominan yang berpengaruh terhadap asfiksia neonatus adalah preeklampsi dengan nilai 24,498 (AOR 24,498; 95%CI; 5,604-107,098), artinya bayi dengan riwayat ibu mengalami preeklamsia memiliki peluang untuk mengalami asfiksia neonatus sebesar 24 kali lebih besar dibandingkan dengan yang tidak preeklamsia. Terdapat kebutuhan mendesak untuk mengembangkan strategi untuk identifikasi dini dan penanganan asfiksia saat lahir dengan melibatkan penerima manfaat, profesional kesehatan, dan pembuat kebijakan. Petugas kesehatan harus dilatih untuk melakukan perawatan obstetrik darurat khususnya penanganan preeklamsia, BBLR, KPD

Download

Plum Print visual indicator of research metrics
PlumX Metrics
  • Usage
    • Downloads: 217
    • Abstract Views: 92
see details

Included in

Epidemiology Commons

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.