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Abstract

TB merupakan tantangan bagi pengendalian Acquired Immunodeficiency Syndrome (AIDS) karena merupakan infeksi oportunistik terbanyak pada orang dengan HIV/AIDS (ODHA). TB dapat meningkatkan progresivitas HIV dan meningkatkan risiko kematian bagi penderita HIV. Tujuan penelitian ini adalah untuk mengetahui prediktor yang berhubungan dengan kejadian TB pada ODHA di salah satu RS tahun 2014-2016. Desain studi yang digunakan adalah cross sectional dengan menggunakan data register ART dan Rekam Medis. Sampel berjumlah 817 pasien HIV. Analisis data dilakukan dengan menggunakan multiple cox regression. Hasil analisis multivariat menunjukkan adanya peningkatan risiko TB pada kelompok dengan anemia (PR=1,54, 95% CI: 1,17-2,03) dibandingkan kelompok tanpa anemia, adanya status IO (PR=5,9, 95% CI: 2,92-11,91) dibandingkan kelompok tanpa IO, stadium HIV 3-4 (PR=8,794, 95% CI: 4,54-17,00) dibandingkan stadium HIV 1-2. Selain itu ditemukan adanya interaksi antara variabel stadium HIV dan status IO. Perlu adanya perhatian khusus kepada ODHA dengan anemia, infeksi oportunis, dan stadium HIV lanjut (3-4) serta perlu perhatian khusus kepada ODHA dengan stadium HIV awal (1-2) tetapi disertai dengan infeksi oportunis

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