Abstract
Peningkatan konsumsi minuman kemasan (soft drinks/ bevereges) tampak nyata di dunia, termasuk Indonesia. Peningkatan ini terutama terjadi di kelompok usia muda. Konsumsi minuman tersebut berkaitan dengan gangguan metabolik, antara lain obesitas, toleransi glukosa terganggu (TGT) dan diabetes melitus. Hal ini disebabkan penggunaan pemanis tinggi fruktosa (high fructose corn syrup, HFCS). TGT terutama menjadi masalah kesehatan serius karena umumnya tidak menunjukkan gejala dan terlambat untuk dideteksi sehingga sering kali telah berprogresi menjadi diabetes mellitus. Penelitian ini bertujuan untuk melihat hubungan konsumsi tinggi fruktosa dengan kejadian TGT pada usia muda, serta prevalensi kekerapan mengkonsumsi minuman tinggi fruktosa, baik secara nasional maupun pada tiap provinsi. Desain penelitian adalah potong lintang yang menggunakan data riset kesehatan dasar (RISKESDAS 2007). Analisis memperlihatkan bahwa konsumsi minuman tinggi fruktosa berhubungan dengan kejadian TGT usia muda setelah mengendalikan kovariat (OR 1,24, p=0,00). Prevalensi TGT pada kelompok usia muda di Indonesia adalah 5,7% dan prevelensi pengkonsumsi fruktosa tinggi sebesar 20,5%. Kontribusi konsumsi fruktosa tinggi terhadap kejadian TGT usia muda adalah 24,3%. Secara umum, prevalensi TGT pada usia muda di Indonesia cukup tinggi dan konsumsi minuman kemasan berpemanis tinggi fruktosa memiliki kontribusi yang signifikan dalam terjadinya TGT.
References
1. Basu S, McKee M, Galea G, Stuckler D. Relationship of Soft Drink Consumption to Global Overweight, Obesity, and Diabetes: A Cross-National Analysis of 75 Countries. Am J Public Health. 2013;103(11):2071–7
2. Vuilleumier S. Worldwide production high-fructose syrupand crystalline fructose. Am J Clin Nutr. 1993;58:S733-736.
3. Dhingra R, Sullivan L, Jacques PF, Wang TJ, Fox CS, MeigsJB, et al. Soft Drink Consumption and Risk of DevelopingCardiometabolic Risk Factors and The Metabolic Syndromein Middle-Aged Adults in the Community. Circulation.2007;116:480–8.
4. Bantle JP, Raatz SK, Thomas W, Georgopoulos A. Effect ofDietary Fructose on Plasma Lipids in Healthy Subjects.Am J Clin Nutr. 2000;72:1128–34.
5. Choi JWJ, Ford ES, Gao X, Choi HK. Sugar-Sweetened SoftDrinks, Diet Soft Drinks, and Serum Uric Acid Level: TheThird National Health and Nutrition Examination Survey.Arthritis Rheum. 2008;58:109–16.
6. Nguyen S, Choi HK, Lustig RH, Hsu CY. Sugar-sweetenedbeverages, serum uric acid, and blood pressure inadolescents. J Pediatr. 2009;154:807–13.
7. Johnson RJ, Segal MS, Sautin Y, Nakagawa T, I Feig D, KangD. Potential role of sugar (fructose) in the epidemic ofhypertension, obesity and the metabolic syndrome,diabetes, kidney disease, and cardiovascular disease. AmJ Clin Nutr. 2007;86:899–906.
8. Brown CM, Dulloo AG, Yepuri G, Montani J. Fructoseingestion acutely elevates blood pressure in healthyyoung humans. Am J Physiol Regul Integr Comp Physiol.2008;294:R730-737.
9. World Health Organization. Definition & Diagnosis ofDiabetes Mellitus and Intermediate Hyperglycemia. WorldHealth Organization; 2006.
10. International Diabetes Federation. Diabetes Atlas. World Diabetes Foundation; 2006. p. 1–381.
11.American Diabetes Association. Diagnosis and Classif ication of Diabetes Mellitus. Diabetes Care. 2004;27:S5-10.
12.The Expert Committee on The Diagnosis and Classification Of Diabetes Mellitus. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care. 2003;26:3160–7.
13. Unwin N, Shaw J, Zimmet P, Alberti KG. Impaired glucose tolerance and impaired fasting glycaemia: the current status on def inition and intervention. Diabet Med. 2002;19:708–23.
14. Badan Penelitian dan Pengembangan Kesehatan Kementrian Kesehatan Republik Indonesia. Laporan Hasil Riset Kesehatan Dasar RISKESDAS Indonesia – Tahun 2007. 2008.
15. Mihardja L, Delima, Siswoyo H, Ghani L, Soegondo S. Prevalence and Determinants of Diabetes Mellitus and Impaired Glucose Tolerance in Indonesia (A Part of Basic Health Research/Riskesdas). Acta Med Indones-Indones J Intern Med. 2009;41:169–74.
16. International Diabetes Foundation. The Global Burden of Diabetes. In: Diabetes Atlas. 2nd ed. 2003. p. 15–107.
17. Doria A. Genetics of Type-2 Diabetes. In: Kahn CR, Weir GC, King GL, Jacobson AM, Moses AC, Smith RJ, editors. Jolin’s Diabetes Mellitus. 14th ed. Boston: Lippincott Williams & Wilkins; 205AD. p. 371–97.
18. Larsen MO, Juhl CB, Pørksen N, Gotfredsen CF, Carr RD, Ribel U, et al. â-Cell function and islet morphology in normal, obese, and obese â-cell mass-reduced Gottingen minipigs. Am J Physiol Endocrinol Metab. 2005;288:E412- 421.
19. Kahn SE, Prigeon RL, Schwartz RS, Fujimoto WY, Knopp RH, Brunzell JD, et al. Obesity, body fat distribution, insulin sensitivity and islet â-cell function as explanation for metabolic diversity. J Nutr. 2001;131:S354-360.
20. Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. â-Cell Deficit and Increase â-Cell Apoptosis in Human With Type 2 Diabetes. Diabetes. 2003;52:102– 10.
21. Elliott SS, Keim NL, Stern JS, Teff K, Havel PJ. Fructose, weight gain, and the insulin resistance syndrome. Am J Clin Nutr. 2002;76:911–22.
22. Jones JM. Dietary Sweeteners Containing Fructose: Overview of a Workshop on the State of the Science. J Nutr. 2009;139:S1210-1213.
23. Vartanian LR, Schwartz MB, Brownell KD. Effects of Soft Drink Consumption on Nutrition and Health: A Systematic Review and Meta-Analysis. Am J Public Heal. 2007;97:667– 75.
24. Gross LS, Li L, Ford ES, Liu S. Increased Consumption of Refine Carbohidrates and the Epidemic of Type 2 Diabetes in the United States: an Ecologic Assessment. Am J Clin Nutr. 2004;79:774–9.
25. Yates T, Khunti K, Bull F, Gorely T, Davies MJ. The role of physical activity in the management of impared glucose tolerance: a systematic review. Diabetologia. 2007;50:1116–26.
26. Henkin L, Zaccaro D, Haffner S, Karter A, Rewers M, Sholinsky P, et al. Cigarette Smoking, Environmental Tobacco Smoke Exposure and Insulin Sensitivity: The Insulin Resistance Atherosclerosis Study. Ann Epidemiol. 1999;9:290–6.
27. Sakai Y, Yamaji T, Tabata S, Ogawa S, Yamaguchi K, Mineshita M, et al. Relation of alcohol use and smoking to glucose tolerance status in Japanese men. Diabetes Res Clin Pr. 2006;73:83–8
Recommended Citation
Lumbuun, Nicolaski and Kodim, Nasrin
(2017)
"Pengaruh Konsumsi Fruktosa pada Minuman Kemasan terhadap Toleransi Glukosa Terganggu pada Kelompok Usia Muda di Perkotaan di Indonesia,"
Jurnal Epidemiologi Kesehatan Indonesia: Vol. 1:
Iss.
2, Article 4.
DOI: 10.7454/epidkes.v1i2.1806
Available at:
https://scholarhub.ui.ac.id/epidkes/vol1/iss2/4
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