Most Common Symptoms of Prediabetic and Insulin Resistance in Adults in Saudi Arabia

Hassan Mazzhar Bukhari, Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah 24381, Saudi ArabiaFollow
Fatoon Mohammed Albuqami, Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah 24381, Saudi ArabiaFollow
Alanoud Mohammed Asiri, Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah 24381, Saudi ArabiaFollow
Ghadeer Othman Yatim, Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah 24381, Saudi ArabiaFollow
Jomana Abdullah Alshareef, Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah 24381, Saudi ArabiaFollow
Ruba Saeed Alzahrani, Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah 24381, Saudi ArabiaFollow

ORCID ID

Hassan Mazzhar Bukhari: 0000-0001-8473-2409

Fatoon Mohammed Albuqami: 0009-0005-7857-8958

Alanoud Mohammed Asiri: 0009-0003-5412-9379

Ghadeer Othman Yatim: 0009-0006-6626-6612

Jomana Abdullah Alshareef: 0009-0009-2461-8669

Ruba Saeed Alzahrani: 0009-0007-7358-3744

Abstract

Background: The prediabetic stage exhibits common symptoms; hence, the risk of developing diabetes can be reduced by identifying these symptoms in the most affected population. This study aimed to examine the prevalence of the main symptoms of insulin resistance in healthy adults aged 18 years and above.

Methods: A cross-sectional study was conducted on 1,514 Saudi adults using an online questionnaire collected from 13th November 2020 to 23rd March 2021. Data on personal, lifestyle, and common symptoms were gathered, and the main symptoms were presented as frequencies with percentages. Association with insulin resistance was evaluated using the Chi-square test and other variables by logistic regression models.

Results: The four most commonly presented symptoms at a frequency of 23% were tiredness after eating, tiredness all day, frequent urination, and thirst even after drinking. When gender and income levels were considered together with insulin resistance levels in the logistic models, only thirst remained a substantial symptom.

Conclusions: In the prediabetic stage, tiredness, urinating more than usual, excessive eating, and thirst were the common symptoms. Implementing public health campaigns and drawing attention to these symptoms for healthcare providers would improve the diagnosis and treatment of diabetes.

References

Tanveer MS, Tanveer MH, Javed M. Type 2 diabetes mellitus in Saudi Arabia: A review of the current situation. J Diabetol. 2021;12:270–4.
Rajab BF, Alamri AE, Alamri AE, Al Yaqoub RF, Ahmed SF. Knowledge toward diabetes risk factors and complications of diabetes mellitus among adults in Jeddah, Saudi Arabia. Int J Med Dev Ctries. 2012;4:223–8.
Petersen MC, Shulman GI. Mechanisms of insulin action and insulin resistance. Physiol Rev. 2018;98:2133–223.
Alam S, Hasan MK, Neaz S, Hussain N, Hossain MF, Rahman T. Diabetes mellitus: Insights from epidemiology, biochemistry, risk factors, diagnosis, complications and comprehensive management. Diabetology. 2021;2:36–50.
Engin S, Akkan T, Dağdeviren M, Şengezer T, Altay M. Are disease-related symptoms important to predicting developing diabetes from prediabetes? Turk J Med Sci. 2022;52:1093–102.
Lawal Y, Bello F, Kaoje YS. Prediabetes deserves more attention: A review. Clin Diabetes. 2020;38:328–38.
Tekir O, Çevik C, Özsezer Kaymak G, Kaya A. The effect of diabetes symptoms on quality of life in individuals with type 2 diabetes. Acta Endocrinol. 2021;17:186–93.
Aedh AI, Alshahrani MS, Huneif MA, Pryme IF, Oruch R. A glimpse into milestones of insulin resistance and an updated review of its management. Nutrients. 2023;15:921.
Ahmed IB, Alateeq FA, Alharbi SH, Ahmed HG. Awareness and knowledge towards type 2 diabetes mellitus risk factors in Northern Saudi Arabia. Int J Med Res Health Sci. 2018;7:33–40.
Ploumen EH, Buiten RA, Kok MM, Doggen CJM, van Houwelingen KG, Stoel MG, et al. Three-year clinical outcome in all-comers with "silent" diabetes, prediabetes, or normoglycemia, treated with contemporary coronary drug-eluting stents: From the BIO-RESORT Silent Diabetes study. Catheter Cardiovasc Interv. 2020;96:E110–8.
Kyrou I, Tsigos C, Mavrogianni C, Cardon G, Van Stappen V, Latomme J, et al. Sociodemographic and lifestyle-related risk factors for identifying vulnerable groups for type 2 diabetes: A narrative review with emphasis on data from Europe. BMC Endocr Disord. 2020;20:134.
Rett K, Gottwald-Hostalek U. Understanding prediabetes: Definition, prevalence, burden and treatment options for an emerging disease. Curr Med Res Opin. 2019;35:1529–34.
Diabetes UK. What are the signs and symptoms of diabetes? United Kingdom: Diabetes UK, 2021.
NHS Inform. Diabetes. Edinburgh: NHS Inform, 2021.
AlKhaldi YM, AlKhaldi AY, AlQahtani AS, Al-Shahrani BS, Meshawi EA, Albishri BM. Incidence of hypoglycemia and its risk factors among diabetics during Ramadan in Abha city, Aseer Region, KSA. J Fam Med Prim Care. 2019;8:2793–8.
Lindström J, Tuomilehto J. The diabetes risk score: A practical tool to predict type 2 diabetes risk. Diabetes Care. 2003;26:725–31.
Bukhari HM. Sociodemographic variables associated with the prevalence of insulin resistance using a non-invasive score system among adults in the Makkah Region of Saudi Arabia. Curr Res Nutr Food Sci. 2023;11:685–95.
Kumar R, Itumalla R, Perera B, Tharwat Elabbasy M, Singh M. Patient knowledge about diabetes: Illness symptoms, complications and preventive personal lifestyle factors. Health Psychol Res. 2022;10:37520.
Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview. Avicenna J Med. 2020;10:174–88.
WebMD. Insulin resistance. New York: WebMD, 2024.
Mayega RW, Rutebemberwa E. Clinical presentation of newly diagnosed diabetes patients in a rural district hospital in Eastern Uganda. Afr Health Sci. 2018;18:707–19.
Romadlon DS, Hasan F, Wiratama BS, Chiu HY. Prevalence and risk factors of fatigue in type 1 and type 2 diabetes: A systematic review and meta-analysis. J Nurs Scholarsh. 2022;54:546–53.
Jain A, Sharma R, Choudhary PK, Yadav N, Jain G, Maanju M. Study of fatigue, depression, and associated factors in type 2 diabetes mellitus in industrial workers. Ind Psychiatry J. 2015;24:179–84.
Clark NG, Fox KM, Grandy S; SHIELD Study Group. Symptoms of diabetes and their association with the risk and presence of diabetes: Findings from the Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD). Diabetes Care. 2007;30:2868–73.
Salari N, Karami MM, Bokaee S, Chaleshgar M, Shohaimi S, Akbari H, et al. The prevalence of urinary tract infections in type 2 diabetic patients: A systematic review and meta-analysis. Eur J Med Res. 2022;27:20.

Recommended Citation

Bukhari HM, Albuqami FM, Asiri AM, Yatim GO, Alshareef JA, Alzahrani RS, et al. Most Common Symptoms of Prediabetic and Insulin Resistance in Adults in Saudi Arabia. Makara J Health Res. 2024;28.