•  
  •  
 

Abstract

Total knee replacement (TKR) is one of the most economical and frequently successful orthopedic procedures. Cost-of-illness studies of TKR in Indonesia are scarce and lack an analysis of the relationship between characteristics and costs. This study aims to examine the cost-of-illness of TKR from a social perspective and explore the relationship between the characteristics and the cost of TKR. This is an observational cross-sectional study of all patients who underwent TKR from 1st January 2022-31 st December 2023. The characteristics were collected from the medical records. Cost of illness was conducted from a social perspective with a bottom-up approach. Hospital cost on the JKN ECLAIM System was obtained as direct medical cost. Direct non-medical and indirect costs were collected through a phone interview with the patient or caregiver. Indirect cost was defined as income loss from the patient and caregiver. The relationship between characteristics and cost was analyzed bivariately using the Mann–Whitney U test and Kruskal–Wallis test. Of a total 54 patient were obtained. Median direct medical cost was 51,769,675 IDR; direct non-medical cost was 850,000 IDR; and indirect cost was 750,000 IDR. None of the characteristics had a direct relationship with medical cost. Age (p = 0.043), Caregiver (p <0.001), and distance traveled (p <0.001) were known as characteristic related to direct non-medical costs. Indirect cost was related to age (p = 0.053) and employment status (p = 0.005). This study only examined the cost of TKR in the hospital. Costs of post-surgery recovery steps, including costs for revisit consultations, wound care, and physiotherapy, need to be carried out in the future.

References

Adeyemi, A., & Trueman, P. (2019) “Economic burden of surgical site infections within the episode of care following joint replacement,” Journal of Orthopedic Surgery and Research, 14(1). https://doi.org/10.1016/j.josr.2019.01.013. Available at: https://doi.org/10.1186/s13018-019-1224-8.

Alodokter (2022) Cari rumah sakit – ortopedi, operasi penggantian lutut [online]. Available at: https://www.alodokter.com/cari-rumah-sakit/ortopedi/operasi-penggantian-lutut?page=1 (Accessed: March 24, 2023).

Gandhi, N. et al. (2023) “Costs and models used in the economic analysis of total knee replacement (TKR): A systematic review,” PLoS ONE, 18(7 July). Available at: https://doi.org/10.1371/journal.pone.0280371.

Hussein, I.H. et al. (2022) “Epidemiology of obese patients undergoing revision total knee arthroplasty: understanding demographics, comorbidities, and propensity weighted analysis of inpatient outcomes.” Journal of the American Academy of Orthopedic Surgeons Global Research and Reviews, 6(2), pp. 123–123. https://doi.org/10.1016/j.jaas.2022.02.0. Available at: https://doi.org/10.5435/JAAOSGlobal-D-21-00263.

Keyvanlo, Z. et al. (2023) “Productivity Loss of Temporary Work Absenteeism Due to COVID-19 and Its Determinant Factors in Northeastern Iran,” Journal of Occupational and Environmental Medicine, 65(10), p. 832. Available at: https://doi.org/10.1097/JOM.0000000000002912.

Kornelsen, J. et al. (2021) “The rural tax: comprehensive out-of-pocket costs associated with patient travel in British Columbia,” BMC Health Services Research, 21(1), 854. https://doi.org/10.1016/j.bhsr.2021.1854. Available at: https://doi.org/10.1186/s12913-021-06833-2.

Kremers, H. et al. (2013) “Determinants of direct medical costs in primary and revision total knee arthroplasty knee,” Clinical Orthopedics and Related Research, 471(1), pp. 206–214. Available at: https://doi.org/10.1007/s11999-012-2508-z.

Marsh, J. et al. (2022) “Health care costs after total knee arthroplasty for satisfied and dissatisfied patients,” Canadian Journal of Surgery, 65(5), E562–E566. Available at: https://doi.org/10.1503/cjs.006721.

Miettinen, H.J.A. et al. (2021) “Health-Related Quality of Life after Hip and Knee Arthroplasty Operations.” Scandinavian Journal of Surgery: SJS: official organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 110(3), pp. 427–433. https://doi.org/10.1016/j.sci.2021.01.03. Available at: https://doi.org/10.1177/1457496920952232.

Molloy, I. B. et al. (2017) “Effects of the length of stay on the cost of total knee and total hip arthroplasty from 2002 to 2013,” Journal of Bone and Joint Surgery - American Volume, 99(5), 402–407. Available at: https://doi.org/10.2106/JBJS.16.00019.

Olickal, J.J. et al. (2023) “Cost-of-illness and associated factors among persons with type 2 diabetes: Findings from a tertiary care center in South India,” Health Policy and Technology, 12(4), 100807. https://doi.org/10.1016/j.hpt.2023.100807. Available at: https://doi.org/10.1016/j.hlpt.2023.100807.

Park, Y. S. et al. (2023) “Association between caregiver type and catastrophic health expenditure among households using inpatient medical services: using Korean health panel,” BMC Health Services Res, 23(1), 721. https://doi.org/10.1016/j.bhsres.2023. Available at: https://doi.org/10.1186/s12913-023-09703-1.

Peel, T.N. et al. (2015) “Direct hospital cost determinants following hip and knee arthroplasty,” Arthritis Care Res. 67, 782–790. Available at: https://doi.org/10.1002/acr.22523.

Qadeer, A.S. et al. (2025) “Economic Evaluation of Total Knee Replacement Compared with Non-Surgical Management for Knee Osteoarthritis in India,” PharmacoEconomics - Open, 9(2), 217–229 Available at: https://doi.org/10.1007/s41669-024-00541-3.

Roche, M. et al. (2018) “Effect of Obesity on Total Knee Arthroplasty Costs and Revision Rate,” Journal of Knee Surgery, 31(1), pp. 38–42. Available at: https://doi.org/10.1055/s-0037-1608933.

Rohrer, F. et al. (2022) “Profit-Influencing Factors in Orthopedic Surgery: An Analysis of Costs and Reimbursements,” Int. J. Environ. Res. Public Health, 19(7), p. 4325. Available at: https://doi.org/10.3390/ijerph19074325.

Ruangsomboon, P. et al. (2025) “Cost-effectiveness of robotic-assisted versus conventional total knee arthroplasty: an analysis from a middle income country,” Acta Orthopaedica, 96, 716–725. https://doi.org/10.1016/j.ao.2025.07.016 Available at: https://doi.org/10.2340/17453674.2025.44753.

Singh, J.A. et al. (2019) “Rates of total joint replacement in the United States: Future projections to 2020–2040 using the national inpatient sample,” J. Rheumatol. Available at: https://doi.org/10.3899/jrheum.170990.

Su, M. et al. (no date) “The direct and indirect effects of length of hospital stay on the costs of inpatients with stroke in Ningxia, China, between and : A retrospective study using quantile regression and structural equation models,” Front. Public Health [Preprint].

Sumargono, E. et al. (no date) “Epidemiology of primary knee replacement in St. Carolus Hospital from 2016 to 2020: a descriptive study.”

Sun, W. et al. (2023) “Changes in epidemiological characteristics of knee arthroplasty in eastern, northern and central China between 2011 and 2020,” Journal of Orthopedic Surgery and Research, 18(1), 104. Available at: https://doi.org/10.1186/s13018-023-03600-3.

Varacallo, M., Luo, T. D., & Johanson, N. A. (2022) “Total Knee Arthroplasty Techniques,” in StatPearls. Treasure Island, Florida: StatPearls Publishing. Available from: http://www.ncbi.nlm.nih.gov/books/NBK499896/ (Accessed: February 23, 2023).

Yoshimura, N. et al. (2012) “Accumulation of metabolic risk factors such as overweight, hypertension, dyslipidaemia, and impaired glucose tolerance raises the risk of occurrence and progression of knee osteoarthritis: a 3-year follow-up of the ROAD study,” Osteoarthritis and Cartilage, Vol. 20 No. 11, pp. 1217–1226. https://doi.org/10.1016/j.oarth.2012.09.016 Available at: https://doi.org/10.1016/j.joca.2012.06.006.

Bahasa Abstract

Prosedur ortopedi yang paling ekonomis dan memiliki tingkat keberhasilan yang tinggi adalah prosedur penggantian lutut total (Total Knee Replacement - TKR). Di Indonesia, eksplorasi studi mengenai biaya penyakit (cost-of-illness) TKR dan analisis karakteristik yang memengaruhinya masih jarang dilakukan. Penelitian ini bertujuan untuk menelaah biaya penyakit TKR dari perspektif sosial dan mengetahui hubungan karakteristik pasien dengan biaya TKR. Studi ini adalah studi observasional (cross-sectional) dari semua pasien yang menjalani TKR pada periode 1 Januari 2022 hingga 31 Desember 2023. Karakteristik dikumpulkan dari rekam medis. Biaya penyakit dihitung dari perspektif sosial dengan pendekatan bawah ke atas (bottom-up). Biaya rumah sakit pada Sistem E-Klaim JKN (Jaminan Kesehatan Nasional) dihitung sebagai biaya medis langsung. Biaya nonmedis langsung dan biaya tidak langsung dikumpulkan melalui wawancara dengan pasien atau pemberi perawatan (caregiver) via telepon. Biaya tidak langsung dihitung sebagai kehilangan pendapatan dari pasien dan pemberi perawatan. Total 54 pasien diperoleh. Median biaya medis langsung adalah Rp 51.769.675; biaya nonmedis langsung Rp 850.000; dan biaya tidak langsung Rp 750.000. Tidak ada karakteristik yang memengaruhi biaya medis langsung. Usia (p = 0.043), pemberi perawatan (caregiver) (p <0.001), dan jarak tempuh (p <0.001) diketahui sebagai karakteristik yang memengaruhi biaya nonmedis langsung. Usia (p = 0.053) dan pekerjaan (p = 0.005) diketahui sebagai faktor yang memengaruhi biaya tidak langsung. Studi ini hanya menelaah biaya TKR di rumah sakit. Biaya pemulihan pascaoperasi, termasuk biaya untuk konsultasi, perawatan luka, dan fisioterapi, perlu dilakukan di masa mendatang.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.