•  
  •  
 

Abstract

Background. As the COVID-19 pandemic occurs, those with asthma were thought to have an increased risk of infection. Question arisen whether special preparation for severe clinical outcomes might be needed for remote site workers. Method. A literature search was conducted through PubMed, Scopus and ProQuest databases, as well as hand searched. The inclusion criteria were systematic review, cohort study, retrospective study, cross sectional study, COVID-19, asthma, and ICU. Then, they were critically appraised based on Center of Evidence-Based Medicine, Oxford University, Critical Appraisal for Prognostic Studies and Systematic Reviews. Result. Three systematic review studies and three retrospective cohort studies were found. Systematic reviews by Sunjaya, et al. (2021) and Hussein, et al. (2021), also retrospective cohort study by Calmes, MD, et al. (2021) showed no significant difference in risk requiring admission to ICU for asthmatic compared to non-asthmatic (RR 1.19; CI 95%: 0.93 – 1.53; p= 0.16), (RR= 1.64, 95%CI = 0.67-3.97; p=0.27), and (OR = 1.4 (95% CI = 0.64-3.2); p =0.39), respectively. Systematic review by Liu (2021), showed no significant difference in asthma prevalence between ICU and non-ICU patients (RR, 1.19; 95% CI, 0.92-1.54; P =0 .17; I2 = 48.6%;). Cohort study by Choi, et al (2020) showed asthma was not a predictive factor for ICU admission in COVID-19 patients (OR 0.656 (95%CI= 0.295 – 1.440); p value =0.302). Contrary, cohort study by Jin, MMed, et.al (2020) showed that COVID-19 patients with asthma had a higher proportion of ICU admission than those who do not have. Conclusion COVID-19 workers with asthma does not have a higher risk of ICU admission.

References

The Centers for Disease Control and Prevention (CDC). Asthma | CDC.

2. Understanding Occupational Asthma: Are You at Risk? | Asthma.net [Internet]. [cited 2021 Apr 1]. Available from: https://asthma.net/living/occupational-risk

3. People with Moderate to Severe Asthma | CDC [Internet]. [cited 2021 Apr 1]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/asthma.html

4. Center for Evidence Based Management. Critical Appraisal of Prognostic Studies [Internet]. [cited 2021 Apr 26]. Available from: https://www.cebm.net/wp-content/uploads/2018/11/Prognosis.pdf

5. Center for Evidence Based Management. Critical Appraisal for Systematic Review [Internet]. [cited 2021 Apr 26]. Available from: https://www.cebm.net/wp-content/uploads/2019/01/Systematic-Review.pdf

6. Armstrong R, Jackson N, Doyle J, Waters E, Howes F. It’s in your hands: The value of handsearching in conducting systematic reviews of public health interventions. Vol. 27, Journal of Public Health. 2005. p. 388–91.

7. Sunjaya AP, Allida SM, Luca Di Tanna G, Jenkins C. Asthma and risk of infection, hospitalization, ICU admission and mortality from COVID-19: Systematic review and meta-analysis. 2021; Available from: https://www.tandfonline.com/action/journalInformation?journalCode=ijas20

8. Hussein MH, Elshazli RM, Attia AS, Nguyen TP, Aboueisha M, Munshi R, et al. Asthma and COVID-19; different entities, same outcome: a meta-analysis of 107,983 patients. Journal of Asthma [Internet]. 2021;0(0):1–8. Available from: https://doi.org/10.1080/02770903.2021.1881970

9. Liu S, Cao Y, Du T, Zhi Y. Prevalence of Comorbid Asthma and Related Outcomes in COVID-19: A Systematic Review and Meta-Analysis. Journal of Allergy and Clinical Immunology In Practice [Internet]. 2021 Feb;9(2):693–701. Available from: https://search.proquest.com/scholarly-journals/prevalence-comorbid-asthma-related-outcomes-covid/docview/2486124193/se-2?accountid=17242

10. Calmes D, Graff S, Maes N, Frix A-N, Thys M, Bonhomme O, et al. Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection. J Allergy Clin Immunol Pract [Internet]. 2021 Jan;9(1):160–9. Available from: https://search.proquest.com/scholarly-journals/asthma-copd-are-not-risk-factors-icu-stay-death/docview/2449959887/se-2?accountid=17242

11. Jin M, Chen C, Huang J, Zhang F, Dong T, Zhang M, et al. Clinical characteristics of COVID-19 patients with asthma in Wuhan, China: a retrospective cohort study. Journal of Asthma. 2020;

12. Choi YJ, Ju-Young P, Lee HS, Suh J, Song JY, Byun MK, et al. Effect of Asthma and Asthma Medication on the Prognosis of Patients with COVID-19. European Respiratory Journal [Internet]. 2021 Feb 4;57(2). Available from: https://search.proquest.com/scholarly-journals/effect-asthma-medication-on-prognosis-patients/docview/2486392602/se-2?accountid=17242

13. OCEBM Levels of EvideThe Oxford 2011 Levels of Evidence Working Group. " ". Oxford Centre for Evidence-Based Medicine; 2011.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.