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Abstract

The laboratory is an experimentation or testing workplace that requires careful behavior in using equipment and material. One of the types of chemicals in the laboratory is an organic solvent as a solvent for other chemicals. The potential risk of breast cancer in female laboratory workers in this cohort study is exposure to organic solvents. Organic solvents that are often used in the laboratory are benzene, toluene, and xylene (BTX). Given workplace exposure to the chemicals benzene, toluene, and xylene, as well as the health hazards posed by these chemicals, a health risk assessment by inhalation using the Singapore SQRA technique is required to assess the amount of risk of chemical exposure to the health of workers at PT. X. Using a questionnaire that corresponds to The German Q18 Questionnaire to collect data on the health complaints of laboratory employees with neurotoxic symptoms. Inhalation and air sampling in the workplace were the first steps in the research. Data from sampling is analyzed to establish the degree of hazard (Hazard Rating), exposure (Exposure Rating), and risk (Risk Rating). Benzene, toluene, and xylene exposure levels were 1.6, 2.0, and 2.1, respectively. Benzene has a danger rating of 3 (moderate), while toluene and xylene have a risk rating of 2 (low risk). In terms of the percentage of respondents with positive neurotoxic symptoms or who answered "yes" to five or more questions on the questionnaire, 25% (1 respondent) and 75% (3 respondents) had negative neurotoxic symptoms.

References

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Bahasa Abstract

Laboratorium merupakan tempat kerja untuk melakukan percobaan atau eksperimen uji dimana bekerja di tempat tersebut membutuhkan perilaku kehati-hatian dalam menggunakan peralatan dan bahan. Salah satu jenis bahan kimia yang terdapat di laboratorium adalah pelarut organik yang memiliki fungsi sebagai pelarut bahan kimia lainnya. Potensi risiko kanker payudara pada pekerja wanita di laboratorium pada studi kohort ini adalah paparan pelarut organik. Pelarut organik yang sering digunakan di laboratorium adalah benzene, toluene dan xylene (BTX). Dengan adanya pajanan bahan kimia benzene, toluene dan xylene di tempat kerja dan risiko kesehatan yang ditimbulkan oleh bahan kimia tersebut, maka perlu dilakukan penilaian tingkat risiko pajanan bahan kimia terhadap kesehatan pekerja di laboratorium PT. X dengan suatu penilaian risiko kesehatan melalui inhalasi dengan menggunakan metode SQRA Singapura. Pengumpulan data terkait dengan keluhan kesehatan pekerja gejala neurotoksik laboratorium menggunakan kuisioner yang mengacu pada The German Q18 Questionnaire. Penelitian dimulai dengan pengambilan sampel inhalasi dan udara di lingkungan kerja. Data hasil sampling diolah untuk mengetahui Tingkat Bahaya (Hazard Rating), Tingkat Pajanan (Exposure Rating), dan Tingkat Risiko (Risk Rating). Nilai tingkat pajanan untuk benzene, toluene dan xylene berturut-turut adalah 1,6;2,0;2,1. Nilai RR benzene adalah 3 (risiko moderat) sedangkan nilai RR toluene dan xylene adalah 2 (risiko rendah). Secara keseluruhan terkait jumlah responden yang memiliki gejala neurotoksik positif atau menjawab “ya” pada 5 pertanyaan atau lebih pada kuisioner sebanyak 25% (1 responden) dan 75% (3 responden) lainnya memiliki gejala neurotoksik negatif.

Kata Kunci: Laboratorium, Neurotoksik, Pajanan Kimia, Semi-Quantutative Risk Assessment (SQRA), Tingkat Risiko

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